A recent study published in JAMA has revealed that low-dose aspirin treatment may not be effective against heart problems in elderly individuals.
The study involved 14, 464 elderly individuals between 60-85 years of age with diabetes mellitus, hypertension and dyslipidemia. The subjects were randomized to receive conventional therapy alone or with aspirin and monitored over 5 years.
No statistically significant benefit was observed in aspirin-treated individuals. The primary point of the study was prevention of non-fatal heart attack, cardiovascular problems and non-fatal stroke. About 2.77% cumulative primary event was observed in treated group compared with 2.96% in non-treated group.
Further studies are planned to analyze the preventive role of aspirin against cancer-related deaths and prevention of cancer recurrence including colorectal carcinoma.