Guaifenesin information from DrugsUpdate
Guaifenesin, an expectorant drug, is prescribed to lower chest congestion as a result of allergies, common cold and other airway infections. Guaifenesin can loosen the mucus plug in bronchus, and helps the body to cough out the mucus.
Pharmacodynamics
No information available
Pharmacokinetics
No information available
Guaifenesin Indications / Guaifenesin Uses
No information available
Guaifenesin Adverse Reactions / Guaifenesin Side Effects
Guaifenesin can cause vomiting, GI upset, nausea, dizziness, headache and mild skin rashes.
Precautions
No information available
Special Precautions
No information available
Other Drug Interactions
No information available
Other Interactions
No information available
Dosage
For Cough (Adults):
For immediate-release formulation, oral dose of 200-400 mg should be administered for every 4 hours. The total dose should not exceed 2.4 g/day. For sustained-release formulations, oral dose of 600-1200 mg should be administered, twice daily. The maximum dose should not exceed 2.4 g/day.
For Cough (Pediatric):
For immediate-release formulations, oral dose of 12 mg/kg/day should be given in 6 divided doses for infants less than 2 years old. For children aged 2-5 years, 50-100 mg oral dose of Guaifenesin should be administered every 4 hours. The maximum dose should not exceed 600 mg/day. For children 6-11 years of age, 100-200 mg oral dose of Guaifenesin should be given, every 4 hours. The maximum dose should not 1.2 g/day. 200-400 mg oral dose of Guaifenesin should be prescribed for individuals 12 years and older, every 4 hours. The maximum dose should not exceed 2.4 g/day.
For sustained-release formulations, for children aged 2-5 years, 300 mg oral dose of Guaifenesin should be administered every 12 hours. The maximum dose should not exceed 600 mg/day. For children 6-11 years of age, 600 mg oral dose of Guaifenesin should be given, every 12 hours. The maximum dose should not 1.2 g/day. 600-1200 mg oral dose of Guaifenesin should be given for individuals 12 years and older, every 12 hours. The maximum dose should not exceed 2.4 g/day.
Food(before/after)
In case of stomach upset, Guaifenesin should be taken with meals
List of Contraindications
Guaifenesin and Pregnancy
USFDA Category C: Guaifenesin may be or may not be harmful to an unborn fetus. Consult a physician if you are in gestation or planning to have a baby during Guaifenesin treatment.
Guaifenesin and Lactation
It is unknown whether Guaifenesin can pass through the breast milk or not. Nursing mothers should consult a physician before taking Guaifenesin.
Guaifenesin and Children
Guaifenesin is contraindicated in children less than four years old. Overdose or toxicity can result in fatal reactions in infants. Intake of plenty of fluids can induce mucus plug lubrication, and loosen the mucus plugs.
Guaifenesin and Geriatic
No specific information
Guaifenesin and Other Contraindications
No specific information
Storage
Store at 20-25°C.
Lab interference
Store at 20-25°C.
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