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Guaifenesin information from DrugsUpdate  

See Available Brands of Guaifenesin in India

Guaifenesin, an expectorant drug, is prescribed to lower chest congestion as a result of allergies, common cold and other airway infections. Guaifenesin can loosen the mucus plug in bronchus, and helps the body to cough out the mucus.

Pharmacodynamics

No information available

Pharmacokinetics

No information available

Guaifenesin Indications / Guaifenesin Uses

No information available

Guaifenesin Adverse Reactions / Guaifenesin Side Effects

Guaifenesin can cause vomiting, GI upset, nausea, dizziness, headache and mild skin rashes.

Precautions

No information available

Special Precautions

No information available

Other Drug Interactions

No information available

Other Interactions

No information available

Dosage

For Cough (Adults):
For immediate-release formulation, oral dose of 200-400 mg should be administered for every 4 hours. The total dose should not exceed 2.4 g/day. For sustained-release formulations, oral dose of 600-1200 mg should be administered, twice daily. The maximum dose should not exceed 2.4 g/day.

For Cough (Pediatric):
For immediate-release formulations, oral dose of 12 mg/kg/day should be given in 6 divided doses for infants less than 2 years old. For children aged 2-5 years, 50-100 mg oral dose of Guaifenesin should be administered every 4 hours. The maximum dose should not exceed 600 mg/day. For children 6-11 years of age, 100-200 mg oral dose of Guaifenesin should be given, every 4 hours. The maximum dose should not 1.2 g/day. 200-400 mg oral dose of Guaifenesin should be prescribed for individuals 12 years and older, every 4 hours. The maximum dose should not exceed 2.4 g/day.

For sustained-release formulations, for children aged 2-5 years, 300 mg oral dose of Guaifenesin should be administered every 12 hours. The maximum dose should not exceed 600 mg/day. For children 6-11 years of age, 600 mg oral dose of Guaifenesin should be given, every 12 hours. The maximum dose should not 1.2 g/day. 600-1200 mg oral dose of Guaifenesin should be given for individuals 12 years and older, every 12 hours. The maximum dose should not exceed 2.4 g/day.

Food(before/after)

In case of stomach upset, Guaifenesin should be taken with meals

List of Contraindications

Guaifenesin and Pregnancy

USFDA Category C: Guaifenesin may be or may not be harmful to an unborn fetus. Consult a physician if you are in gestation or planning to have a baby during Guaifenesin treatment.

Guaifenesin and Lactation

It is unknown whether Guaifenesin can pass through the breast milk or not. Nursing mothers should consult a physician before taking Guaifenesin.

Guaifenesin and Children

Guaifenesin is contraindicated in children less than four years old. Overdose or toxicity can result in fatal reactions in infants. Intake of plenty of fluids can induce mucus plug lubrication, and loosen the mucus plugs.

Guaifenesin and Geriatic

No specific information

Guaifenesin and Other Contraindications

No specific information

Storage

Store at 20-25°C.

Lab interference

Store at 20-25°C.

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