P - Caution when used during Pregnancy.
Buclizine is an antihistamine and anticholinergic of the piperazine derivative family. It is considered to be an antiemetic, similar to meclozine.
Buclizine is a piperazine antihistamine with antimuscarinic and moderate sedative properties. It is used mainly for its antiemetic action and in the treatment of migraine in combination with analgesics.
It is used as prophylaxis of motion sickness; in the treatment of migraine, nausea, vomiting and pruritic skin disorders.
Drowsiness, dizziness, incoordination; blurred vision; urinary retention; vomiting; rash; dry mouth; headache, nausea, epigastric pain, wt gain and diarrhoea.
Driving or operating machinery; open-angle glaucoma; urinary retention; prostatic hyperplasia, pyloroduodenal obstruction, epilepsy; renal and hepatic impairment; pregnancy.
Potentially Fatal: Effect of alcohol, sedatives and other CNS depressants potentiated.
Should be taken with food. (Take w/in ½ hr before meals.)
Potentially Fatal: EffeCategory C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.ct of alcohol, sedatives and other CNS depressants potentiated.