Sodium Chloride information from DrugsUpdate
P - Contraindicated in pregnancy
L - Caution when used during lactation
Sodium chloride, also known as salt, common salt, table salt, or halite, is an ionic compound with the formula NaCl. Sodium chloride is the salt most responsible for the salinity of the ocean and of the extracellular fluid of many multicellular organisms. As the major ingredient in edible salt, it is commonly used as a condiment and food preservative.
Sodium Chloride injection products are sterile, nonpyrogenic solutions of electrolytes in water for injection intended only for sterile irrigation, washing, rinsing and dilution purposes.
Sodium chloride, a chemical name of common salt, is used to treat and prevent sodium loss (hyponatremia) due to excessive sweating, dehydration and other similar causes. Sodium chloride is a vital electrolyte that regulates the levels of body fluids. Sodium chloride is important for muscular contractions and regulation of nerve impulses.
Pharmacodynamics
Pharmacokinetics
Information Not Available
Sodium Chloride Indications / Sodium Chloride Uses
Information Not Available
Sodium Chloride Adverse Reactions / Sodium Chloride Side Effects
Hypernatraemia, thirst, reduced salivation and lachrymation, fever, tachycardia, hypertension, headache, dizziness, restlessness, irritability and weakness. Intra-amniotic inj of hypertonic solutions: Disseminated intravascular coagulation, renal necrosis, cervical and uterine lesions, pulmonary embolism, pneumonia and death.
Precautions
Hypertension, heart failure, peripheral or pulmonary oedema, impaired renal function, liver cirrhosis, preeclampsia. Maintain adequate water intake. Sodium chloride is contraindicated in patients with electrolyte imbalance, CHF, hypertension, renal disorders, hepatic cirrhosis, pleural effusion, fluid retention, preeclampsia, allergic to synthetic foods and in patients who are on low-salt diet.
Special Precautions
Pregnancy: Inj of 3 or 5% NaCl solution should be given through a large vein at a rate not exceeding 100ml/hr. Monitor fluid balance, serum electrolytes and acid base balance especially during prolonged treatment. Caution when used in patients who are receiving corticosteroids or corticotropin.
Other Drug Interactions
Drug Interactions
Additives may be incompatible. Consult with pharmacist, if available. When introducing additives, use aseptic technique, mix thoroughly and do not store.
Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution container permits.
Other Interactions
May affect serum concentrations of lithium
Dosage
Nasal congesation:
Adult: 0.9% used as nasal drops or spray.
Child: 0.9% as nasal drops.
Food(before/after)
Information Not Available
List of Contraindications
Sodium Chloride and Pregnancy
Teratogenic Effects
Pregnancy Category C. Animal reproduction studies have not been conducted with Sodium Chloride Irrigation, USP. It is also not known whether Sodium Chloride Irrigation, USP can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Sodium Chloride Irrigation, USP should be given to a pregnant woman only if clearly needed.
Sodium Chloride and Lactation
Caution should be exercised when Sodium Chloride Irrigation, USP is administered to a nursing woman.
Sodium Chloride and Children
Safety and effectiveness of Sodium Chloride irrigation solution in pediatric patients have not been established by adequate and well-controlled trials. However, the use of Sodium Chloride irrigation solution in the pediatric population is referenced in the medical literature. The Warnings, Precautions, and Adverse Reactions identified in the label should be observed in the pediatric population.
Sodium Chloride and Geriatic
An evaluation of current literature revealed no clinical experience identifying differences in response between elderly and younger patients.
This drug is known to be substantially secreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function.
Sodium Chloride and Other Contraindications
Information Not Available
Storage
Store at 20-25°C.
Lab interference
Store at 20-25°C.
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