Bezafibrate information from DrugsUpdate
Bezafibrate (marketed as Bezalip and various other brand names) is a fibrate drug used for the treatment of hyperlipidaemia. It helps to lower LDL cholesterol and triglyceride in the blood, and increase HDL.
Pharmacodynamics
Pharmacokinetics
Information Not Available
Bezafibrate Indications / Bezafibrate Uses
Information Not Available
Bezafibrate Adverse Reactions / Bezafibrate Side Effects
GI upset, pruritus, urticaria, alopoecia, impotence; vertigo, fatigue; increased serum transminases. Leucopenia,thrombocytopenia; myotoxicity.
Precautions
Information Not Available
Special Precautions
Renal impairement, children. In patients receiving chlestyramine, the two drugs must be separated by twp hours. History of jaundice or hepatic disorder; renal impairement (reduce dose) hypoalbumineamia or nephrotic syndrome.
Other Drug Interactions
Chlorestyramine inhibits bezafibrate absorption. Enhanced effects of oral anticoagulants
Other Interactions
Information Not Available
Dosage
Oral
Hyperlipidaemias:
Adult- 200mg tid may increase dose gradually over 5-7 days. Maintenance : 200 mg bid. As modified – release preparation: 400mg daily.
Food(before/after)
Should be taken with food
List of Contraindications
Bezafibrate and Pregnancy
Information Not Available
Bezafibrate and Lactation
Information Not Available
Bezafibrate and Children
Information Not Available
Bezafibrate and Geriatic
Information Not Available
Bezafibrate and Other Contraindications
Advanced liver disease, primary biliary cirrhosis; gallstones or gall blader disorders; severe renal insufficiency, hypoalbumineamia or nephrotic syndrome.
Storage
Information Not Available
Lab interference
Information Not Available
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