Betahistine information from DrugsUpdate
P - Cautioned while taken during pregnancy
L - Cautioned while taken during lactation
Betahistine hydrochloride is the generic name for the anti vertigo drug SERC. It was first registered in Europe in 1970 for the treatment of Ménière's disease. It is commonly prescribed for people who have balance disorders or to alleviate the vertigo symptoms associated with Ménière's disease.
Betahistine is available in 8mg, 16mg, or 24mg tablets. It is contraindicated for people with peptic ulcers or tumours of the adrenal gland. People with bronchial asthma should be closely monitored.
Pharmacodynamics
Pharmacokinetics
Betahistine improves the microcirculation in the labyrinth which reduces endolymphatic pressure.
Absorption: Rapid and complete.
Metabolism: Hepatic.
Excretion: Urine (as inactive metabolites); 3.4 hr (elimination half-life).
Betahistine Indications / Betahistine Uses
Information Not Available
Betahistine Adverse Reactions / Betahistine Side Effects
Rash, pruritus, urticaria, dyspepsia, nausea, peptic ulcer disease, headache, dizziness, insomnia
Precautions
Information Not Available
Special Precautions
Active peptic ulcer, bronchial asthma, pregnancy and lactation
Other Drug Interactions
May antagonise antihistamines. May decrease bronchodilator effects of β-2 agonists.
Other Interactions
Information Not Available
Dosage
Oral
Meniere's disease
Adult: Initially, 16 mg tid. Maintenance: 24-48 mg daily
Food(before/after)
Should be taken with food
List of Contraindications
Betahistine and Pregnancy
Caution when used during pregnancy
Betahistine and Lactation
Caution when used during lactation
Betahistine and Children
Information Not Available
Betahistine and Geriatic
Information Not Available
Betahistine and Other Contraindications
Phaeochromocytoma. Porphyria
Storage
Oral: Store below 25°C
Lab interference
Oral: Store below 25°C
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