Diclofenac + Paracetamol information from DrugsUpdate  

Pharmacodynamics

Pharmacokinetics

Diclofenac is a NSAID (NSAID). Paracetamol is an analgesic and antipyretic. When used together, the actions of paracetamol set in earlier and provides pain relief before the effects of diclofenac Na set in.

Diclofenac + Paracetamol Indications / Diclofenac + Paracetamol Uses

Information Not Available

Diclofenac + Paracetamol Adverse Reactions / Diclofenac + Paracetamol Side Effects

GI disturbances, nephrotic syndrome, epigastric pain, nausea, vomiting, diarrhoea, hepatitis, rash, pruritus, wheezing, bronchospasm, prolonged bleeding time.

Potentially Fatal: Bleeding or perforation through peptic ulcer, rarely blood dyscrasia or anaphylaxis, acute renal failure.

Precautions

Information Not Available

Special Precautions

Analgesic nephropathy, renal or hepatic impairment, hypertension, cardiac failure, bronchospasm, patients taking diuretics and elderly, lactation.

Other Drug Interactions

Potentiates potassium-sparing diuretics. Reduced serum levels of salicylates.

Potentially Fatal: Increased levels of lithium, digoxin and methotrexate.

Other Interactions

Information Not Available

Dosage

Oral
Pain and inflammation associated with musculoskeletal and joint disorders
Adult: Per tablet contains diclofenac sodium 50 mg and paracetamol 500 mg. 1 tablet tid.

Food(before/after)

Information Not Available

Diclofenac + Paracetamol and Pregnancy

Caution when used during pregnancy

Diclofenac + Paracetamol and Lactation

Caution when used during lactation

Diclofenac + Paracetamol and Children

Information Not Available

Diclofenac + Paracetamol and Geriatic

Information Not Available

Diclofenac + Paracetamol and Other Contraindications

Hypersensitivity, active peptic ulcer or GI bleeding, history of allergic responses to aspirin or other NSAIDs, acute porphyria.

Storage

Information Not Available

Lab interference

Information Not Available