Olopatadine information from DrugsUpdate
P - Caution when used during pregnancy
L - Caution when used during lactation
Olopatadine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of itching or watery eyes.
Pharmacodynamics
Pharmacokinetics
Olopatadine is a relatively selective histamine H1-receptor antagonist and inhibits the release of histamine from mast cells. It shares many of the pharmacologic effects of mast cell stabilisers.
Olopatadine Indications / Olopatadine Uses
Information Not Available
Olopatadine Adverse Reactions / Olopatadine Side Effects
Headache; asthenia; cold syndrome; pharyngitis; rhinitis; sinusitis; dysgeusia; ocular burning or stinging; dry eye; foreign body sensation; hyperaemia; keratitis; lid oedema; ocular pruritus; blurred vision.
Precautions
Monitor
Preform nasal examinations periodically (intranasal)
Special Precautions
Remove contact lenses prior to admin. Reinsert soft contact lenses 10 min after admin. Pregnancy, lactation.
Other Drug Interactions
Information Not Available
Other Interactions
Information Not Available
Dosage
Ophthalmic
Allergic Conjunctivitis
Adult: As 0.1% solution: 1 or 2 drops in the affected eye(s) bid at an interval of 6-8 hours. Alternatively, as a 0.2% solution: 1 drop in the affected eye(s) once daily.
Child: ≥3 years: As 0.1% solution: 1 or 2 drops in the affected eye(s) bid at an interval of 6-8 hours. Alternatively, as a 0.2% solution: 1 drop in the affected eye(s) once daily.
Food(before/after)
Information Not Available
List of Contraindications
Olopatadine and Pregnancy
Caution when used during pregnancy
Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.
Olopatadine and Lactation
Caution when used during lactation
Olopatadine and Children
Safety and effectiveness in children younger than 3 years of age are not established (ophthalmic); safety and effectiveness in children younger than 12 years of age not established (intranasal).
Olopatadine and Geriatic
No differences in safety or effectiveness observed; however, use caution in dose selection, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.
Olopatadine and Other Contraindications
Hypersensitivity; children <3 years
Storage
Ophthalmic
Store at 2-25°C.
Lab interference
Ophthalmic
Store at 2-25°C.
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