P - Caution when used during pregnancy
L - Caution when used during lactation
FI - Food*
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Ibuprofen is a potent anti-inflammatory with analgesic and antipyretic action. Its analgesic and antipyretic effects are further reinforced by paracetamol.
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Dyspepsia, heart burn, GI bleeding, rash, asthmatic attacks, thrombocytopenia, drug induced ulcer, drowsiness, hepatic necrosis, renal papillary necrosis, vision disturbances & disorientation; rarely nausea & vomiting can occur.
Potentially Fatal: Hematemesis, agranulocytosis, severe allergic reaction.
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Bronchial asthma, renal or hepatic disorders, bleeding disorders, CV diseases, hypertension, patients on anticoagulants, aspirin/NSAIDs induced allergy, pregnancy & lactation.
Ibuprofen antagonises the effects of furosemide & thiazides. Pethidine & propanthelene reduce absorption of paracetamol. Aspirin displaces ibuprofen from binding sites. NSAIDs blunt the effects of antihypertensives.
Potentially Fatal: Increased risk of GI ulceration & bleeding with anticoagulants. Paracetamol increases the risk of liver damage in chronic alcoholics. Ibuprofen increases the risk of methotrexate toxicity & lithium toxicity.
Food Interaction
Food interferes with the rate of ibuprofen absorption
Oral
Pain and inflammation associated with musculoskeletal and joint disorders
Adult: (Ibuprofen 400 mg + Paracetamol 325/500 mg) 1 tab 3-4 times daily.
Child: (Ibuprofen 100mg + Paracetamol 125mg) 1 dose tid or as required.
Information Not Available
Caution when used during pregnancy
Caution when used during lactation
Information Not Available
Information Not Available
Active peptic ulcer, history of hypersensitivity to either component, recent GI bleeding, neonates.
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You will hear from us only if the bid amount matches the minimum threshold and intended usage match our vision. You can resubmit another bid.