Clonidine + Hydro-chlorothiazide information from DrugsUpdate
P - Caution when used during pregnancy
L - Caution when used during lactation
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Pharmacodynamics
Pharmacokinetics
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Clonidine + Hydro-chlorothiazide Indications / Clonidine + Hydro-chlorothiazide Uses
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Clonidine + Hydro-chlorothiazide Adverse Reactions / Clonidine + Hydro-chlorothiazide Side Effects
Electrolyte imbalance, pancreatitis, jaundice, diarrhoea, vommiting, cramps, constiption, gastric irritation, nausea, anorxia, aplastic anaemia, agranulocytosis, leukopaenia, haemolytic anaemia, thrombocytopaenia, analphylatic reactions, vascultis, resp distress including pneumonitis & pulmonary oedema, photosensitivity, fever, urticaria, rash, purpura, hyperglycaemia, glycosuria, hyperuricaemia, vertigo, paraesthesias, dizziness, headache, restlessness, renal failure, renal dysfunction, interstitial nephritis, erthyema multiforme including Stevens- Johnson syndrome, exfoliative dermatitis including toxic epidermal necrolysis, alopecia, transient blurred vision,xanthopsia, impotence. Severe Hypotension.
Precautions
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Special Precautions
Gradual withdrawal, elderly, severe renal disease, impaired hepatic function, allergy or bronchial asthama, systemic lupus erthyematosus, acute gout, diabetes mellitus, cardiac arrhythmias, pregnancy, lactation.
Other Drug Interactions
Hypesedatives, alcohol, antihistamines may cause excessive drowsiness. In combination with alcohol , barbiturates or narcotics risk of orthostatic hypotension is increased. Antihypertensive gives additive effect. Absorption is reduced with chloestyramine & colestipol resins. Hypokalaemia is observed with corticosteroids. Tubocurarine responsiveness is increased. NSAIDs reduces the dieurtic & natriuretic effect. Diuretics decrease renal clearence of lithium.
Other Interactions
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Dosage
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Food(before/after)
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List of Contraindications
Clonidine + Hydro-chlorothiazide and Pregnancy
Caution when used during pregnancy
Clonidine + Hydro-chlorothiazide and Lactation
Caution when used during lactation
Clonidine + Hydro-chlorothiazide and Children
Information Not Available
Clonidine + Hydro-chlorothiazide and Geriatic
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Clonidine + Hydro-chlorothiazide and Other Contraindications
Anuria, Hypersensitivity disorders of cardiac pacemaker activity & conduction.
Storage
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Lab interference
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