P - Contraindicated in pregnancy
L - Contraindicated in lactation
Aceclofenac is a non-steroidal anti-inflammatory drug. It is manufactured by Intas Biopharmaceuticals, under the tradename Hifenac in various forms (tablets, gel, injection etc.). Another trade name is Acetal. It is used for the relief of pain and inflammation in rheumatoid arthritis, osteoarthritis and ankylosing spondylitis.
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Diarrhoea, nausea, dyspepsia, abdominal pain, dizziness, rashes; inceased LFTs. Severe GI bleeding; nephrotoxicity; blood dyscrasias.
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Cautiously administer to patients with GI diease, ulceratove colitis, Crohn`s disease, haematological abnormalities, hepatic porphyria; history of bronchial asthama, history of heart failure or hypertension; mild renal hepatic or cardiac impairment. May impair ability to drive or operate machinery. Elderly.
May increase plasma concentrations of lithium and digoxin. Increased nephrotoxicity when used with diuretics or ciclosporin. Monitor serum potassium when used with potassium-sparing diuretics and ACE inhibitors. May enhance activity of anticoagulants. May increase risk of methotrexate toxicity when administered within 24 hr of methotrexate admin. Increased risk of GI bleed with other NSAIDs. Increased risk of convulsion with quinolones.
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Oral
Ankylosing spondylitis, Rheumatoid arthritis, Osteoarthritis
Adult: 100 mg bid.
Hepatic impairment: Reduce initial dose to 100 mg daily .
Take with or immediately after meals.
Contraindicated in pregnancy.
It should not be given to people with porphyria or breast-feeding mothers.
Not recommended for children.
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Hypersensitivity to aspirin or NSAIDs; moderate to severe renal impairment; pregnancy (third trimester); history of peptic ulceration or GI bleed; patients with infections.
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You will hear from us only if the bid amount matches the minimum threshold and intended usage match our vision. You can resubmit another bid.
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