Aceclofenac information from DrugsUpdate
P - Contraindicated in pregnancy
L - Contraindicated in lactation
Aceclofenac is a non-steroidal anti-inflammatory drug. It is manufactured by Intas Biopharmaceuticals, under the tradename Hifenac in various forms (tablets, gel, injection etc.). Another trade name is Acetal. It is used for the relief of pain and inflammation in rheumatoid arthritis, osteoarthritis and ankylosing spondylitis.
Pharmacodynamics
Pharmacokinetics
Information Not Available
Aceclofenac Indications / Aceclofenac Uses
Information Not Available
Aceclofenac Adverse Reactions / Aceclofenac Side Effects
Diarrhoea, nausea, dyspepsia, abdominal pain, dizziness, rashes; inceased LFTs. Severe GI bleeding; nephrotoxicity; blood dyscrasias.
Precautions
Information Not Available
Special Precautions
Cautiously administer to patients with GI diease, ulceratove colitis, Crohn`s disease, haematological abnormalities, hepatic porphyria; history of bronchial asthama, history of heart failure or hypertension; mild renal hepatic or cardiac impairment. May impair ability to drive or operate machinery. Elderly.
Other Drug Interactions
May increase plasma concentrations of lithium and digoxin. Increased nephrotoxicity when used with diuretics or ciclosporin. Monitor serum potassium when used with potassium-sparing diuretics and ACE inhibitors. May enhance activity of anticoagulants. May increase risk of methotrexate toxicity when administered within 24 hr of methotrexate admin. Increased risk of GI bleed with other NSAIDs. Increased risk of convulsion with quinolones.
Other Interactions
Information Not Available
Dosage
Oral
Ankylosing spondylitis, Rheumatoid arthritis, Osteoarthritis
Adult: 100 mg bid.
Hepatic impairment: Reduce initial dose to 100 mg daily .
Food(before/after)
Take with or immediately after meals.
List of Contraindications
Aceclofenac and Pregnancy
Contraindicated in pregnancy.
Aceclofenac and Lactation
It should not be given to people with porphyria or breast-feeding mothers.
Aceclofenac and Children
Not recommended for children.
Aceclofenac and Geriatic
Information Not Available
Aceclofenac and Other Contraindications
Hypersensitivity to aspirin or NSAIDs; moderate to severe renal impairment; pregnancy (third trimester); history of peptic ulceration or GI bleed; patients with infections.
Storage
Information Not Available
Lab interference
Information Not Available
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