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Sulfacetamide information from DrugsUpdate  

See Available Brands of Sulfacetamide in India

P - Caution when used during pregnancy
L - Caution when used during lactation
LI - Lab *

Sulfacetamide is a sulfonamide antibiotic.

Pharmacodynamics

Pharmacokinetics

Sulfacetamide has bacteriostatic effect on a wide range of gram-positive and gram-negative organisms. It interferes with nucleic acid synthesis thus blocking conversion of PABA to the coenzyme dihydrofolic acid.

Absorption

Penetrates into ocular tissues and fluids (ophthalmic).

Excretion

Urine (as unchanged drug); 7-13 hours (elimination half-life).

Sulfacetamide Indications / Sulfacetamide Uses

Information Not Available

Sulfacetamide Adverse Reactions / Sulfacetamide Side Effects

Hypersensitivity skin reaction. Ophthalmic: Burning, stinging, conjunctivitis, corneal ulcers, irritation, conjunctival hyperaemia. Systemic absorption from inflamed conjunctiva.

Potentially Fatal: Stevens-Johnson syndrome.

Precautions

Prolonged use of topical anti-bacterial agents may give rise to overgrowth of nonsusceptible organisms including fungi. Bacterial resistance to sulfonamides may also develop.

Special Precautions

Elderly. History of allergy or asthma; G6PD deficiency; renal and hepatic impairment. Prolonged therapy requires CBC and urinalysis with microscopic examination. Maintain adequate fluid intake. Pregnancy, lactation.

Other Drug Interactions

Action antagonised by PABA and procaine group of local anaesthetics. PABA present in purulent eye exudates can competitively inhibit the action of sulphacetamide.

Other Interactions

Information Not Available

Dosage

Ophthalmic
Ocular infections
Adult: As sodium: Apply 10-30% eye drops or 10% ointment into the affected eye/s. May be used up to tid.

Food(before/after)

Information Not Available

List of Contraindications

Sulfacetamide and Pregnancy

Caution when used during pregnancy

Sulfacetamide and Lactation

Caution when used during lactation

Sulfacetamide and Children

Information Not Available

Sulfacetamide and Geriatic

Information Not Available

Sulfacetamide and Other Contraindications

Hypersensitivity; infants <2 months

Storage

Ophthalmic
Store below 25°C.

Lab interference

Ophthalmic
Store below 25°C.

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