P - Caution when used during pregnancy
L - Caution when used during lactation
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S-Atenolol selectively blocks the β1 receptors, and it significantly reduces both maximal and submaximal exercise heart rates in a dose-related manner. Endocrine and metabolic actions of S-atenolol include lowering of plasma renin activity and free fatty acids.
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Fatigue, cold extremities, bradycardia, heart failure, headache, dizziness, hallucinations, confusion and sleep disturbances.
Overdosage
May cause severe and fatal CV depression. Activated charcoal or gastric lavage may be considered if patient presents within 1 hr of ingestion.
Renal failure, DM, children, pregnancy and lactation. May mask symptoms of hyperthyroidism and hypoglycaemia. Avoid abrupt withdrawal.
Disopyramide when given in combination with atenolol depresses myocardial contractility and may precipitate cardiac failure. Efficacy may be antagonised by NSAIDs.
Potentially Fatal: Concurrent use with verapamil may precipitate heart failure in patients with impaired left ventricular function. Simultaneous withdrawal of atenolol and clonidine may result in severe rebound hypertension.
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Oral
Hypertension
Adult: 50-100 mg once daily.
Renal impairment: Dosage adjustments may be required.
Oral
Angina pectoris
Adult: 50-100 mg once daily.
Renal impairment: Dosage adjustments may be required.
Oral
Prophylaxis of migraine
Adult: 50-100 mg daily.
Renal impairment: Dosage adjustments may be required.
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Caution when used during pregnancy
Caution when used during lactation
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Hypersensitivity, 2nd and 3rd degree heart block, cardiogenic shock, bronchospasm, history of obstructive airway disease, metabolic acidosis, hypotension, severe peripheral arterial disease, sinus bradycardia.
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You will hear from us only if the bid amount matches the minimum threshold and intended usage match our vision. You can resubmit another bid.