S- Atenolol information from DrugsUpdate
P - Caution when used during pregnancy
L - Caution when used during lactation
Information Not Available
Pharmacodynamics
Pharmacokinetics
S-Atenolol selectively blocks the β1 receptors, and it significantly reduces both maximal and submaximal exercise heart rates in a dose-related manner. Endocrine and metabolic actions of S-atenolol include lowering of plasma renin activity and free fatty acids.
S- Atenolol Indications / S- Atenolol Uses
Information Not Available
S- Atenolol Adverse Reactions / S- Atenolol Side Effects
Fatigue, cold extremities, bradycardia, heart failure, headache, dizziness, hallucinations, confusion and sleep disturbances.
Precautions
Overdosage
May cause severe and fatal CV depression. Activated charcoal or gastric lavage may be considered if patient presents within 1 hr of ingestion.
Special Precautions
Renal failure, DM, children, pregnancy and lactation. May mask symptoms of hyperthyroidism and hypoglycaemia. Avoid abrupt withdrawal.
Other Drug Interactions
Disopyramide when given in combination with atenolol depresses myocardial contractility and may precipitate cardiac failure. Efficacy may be antagonised by NSAIDs.
Potentially Fatal: Concurrent use with verapamil may precipitate heart failure in patients with impaired left ventricular function. Simultaneous withdrawal of atenolol and clonidine may result in severe rebound hypertension.
Other Interactions
Information Not Available
Dosage
Oral
Hypertension
Adult: 50-100 mg once daily.
Renal impairment: Dosage adjustments may be required.
Oral
Angina pectoris
Adult: 50-100 mg once daily.
Renal impairment: Dosage adjustments may be required.
Oral
Prophylaxis of migraine
Adult: 50-100 mg daily.
Renal impairment: Dosage adjustments may be required.
Food(before/after)
Information Not Available
List of Contraindications
S- Atenolol and Pregnancy
Caution when used during pregnancy
S- Atenolol and Lactation
Caution when used during lactation
S- Atenolol and Children
Information Not Available
S- Atenolol and Geriatic
Information Not Available
S- Atenolol and Other Contraindications
Hypersensitivity, 2nd and 3rd degree heart block, cardiogenic shock, bronchospasm, history of obstructive airway disease, metabolic acidosis, hypotension, severe peripheral arterial disease, sinus bradycardia.
Storage
Information Not Available
Lab interference
Information Not Available
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