Econazole information from DrugsUpdate
P - Caution when used during pregnancy
Econazole nitrate is an antifungal medication of the imidazole class. It is used as a cream under the brand names Spectazole (US), Ecostatin (Canada) and Pevaryl (Western Europe) to treat skin infections such as athlete's foot, tinea or pityriasis versicolor, ringworm, and jock itch.
Pharmacodynamics
Pharmacokinetics
Econazole modifies the permeability of cell wall membrane in fungi; may interfere with RNA and protein synthesis, and lipid metabolism. Absorption Insignificant (topical or vaginal).
Econazole Indications / Econazole Uses
Information Not Available
Econazole Adverse Reactions / Econazole Side Effects
Vulvar/vaginal burning; burning sensation; erythema; itching; contact dermatitis
Precautions
Information Not Available
Special Precautions
Avoid contact with eyes and mucous membranes. May damage latex contraceptives. Pregnancy.
Other Drug Interactions
Information Not Available
Other Interactions
Information Not Available
Dosage
Vaginal Vaginal candidiasis Adult: 150 mg pessaries once daily at bedtime for 3 consecutive nights or a single dose of 150 mg (as a long-acting formulation). Alternatively, 5 g of 10% cream every night for 2 wk. Topical/Cutaneous Skin fungal infections Adult: Apply 1% cream, lotion, powd or soln up to tid. Continue for 2-4 wk. Child: Same as adult dose. Topical/Cutaneous Nail fungal infections Adult: As 1% cream/lotion: Apply once daily under occlusive dressing.
Food(before/after)
Information Not Available
List of Contraindications
Econazole and Pregnancy
Caution when used during pregnancy. Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.
Econazole and Lactation
Information Not Available
Econazole and Children
Information Not Available
Econazole and Geriatic
Information Not Available
Econazole and Other Contraindications
Hypersensitivity. Porphyria; pregnancy
Storage
Topical/Cutaneous Store below 30 ℃ Vaginal Store below 30 ℃
Lab interference
Topical/Cutaneous Store below 30 ℃ Vaginal Store below 30 ℃
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