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Benidipine information from DrugsUpdate  

See Available Brands of Benidipine in India

P - Contraindicated in pregnancy
L - Contraindicated in lactation

Benidipine, also known as Benidipinum or benidipine hydrochloride, is a dihydropyridine calcium channel blocker for the treatment of high blood pressure (hypertension).

Pharmacodynamics

Pharmacokinetics

The vasorelaxant effect of benidipine is due to its affinity towards dihydropyridine binding sites in calcium channels. Binding of benidipine with calcium channels inhibits calcium current. The onset of action is slow, which results in minimal tachycardia or palpitation.

Benidipine Indications / Benidipine Uses

Information Not Available

Benidipine Adverse Reactions / Benidipine Side Effects

Palpitation, facial flushing, hot flushes, chest pressure sensation, headache, dizziness, sleepiness, constipation, nausea, abdominal discomfort, oedema, malaise, tinnitus, redness and warm feeling in the fingers, shoulder stiffness, increased frequency of micturition. Hypersensitive reactions e.g. rash and itching. Elevation of SGOT, SGPT, alkaline phosphatase, total bilirubin, creatinine and uric acid.

Precautions

Information Not Available

Special Precautions

Elderly. In case of dizziness or lightheadedness, advise patients against handling of heavy machines or working at elevated spots. Reduce dosage gradually while withdrawing drug. Liver function tests.

Other Drug Interactions

β-blockers or diuretics may enhance BP control. Serum concentrations of digoxin may be increased. Cimetidine may inhibit benidipine metabolism.

Other Interactions

Information Not Available

Dosage

Oral Hypertension Adult: 2-4 mg once daily increased to 8 mg once daily, if necessary. Oral Angina Pectoris Adult: 4 mg bid.

Food(before/after)

Should be taken with food

List of Contraindications

Benidipine and Pregnancy

Contraindicated in pregnancy

Benidipine and Lactation

Contraindicated in lactation

Benidipine and Children

Information Not Available

Benidipine and Geriatic

Information Not Available

Benidipine and Other Contraindications

Pregnancy and lactation

Storage

Information Not Available

Lab interference

Information Not Available

Benidipine brands in India:

Caritec

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