Benfotiamine (rINN, or S-benzoylthiamine O-monophoshate) is a synthetic S-acyl derivative of thiamine (vitamine B1). After absorption, benfotiamine can be dephosphorylated by cells bearing an ecto-alkaline phosphatase to the lipid-soluble S-benzoylthiamine. Benfotiamine should not be confused with allithiamine, a naturally occurring thiamine disulfide derivative with a distinct pharmacological profile.
Benfotiamine is an allithiamine that boosts Advanced Glycation Endproduct (AGE)-inhibiting thiamine pyrophosphate and cell-shielding transketolase activity.
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Oral Diabetic neuropathy, Alcoholic neuropathy Adult: 100 mg 4 times daily.
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Hypersentivity
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