logo image

Azelastine information from DrugsUpdate  

See Available Brands of Azelastine in India

P - Caution when used during pregnancy
L - Caution when used during lactation

Azelastine is an antihistamine and mast cell stabilizer available as a nasal spray (Astelin or Astepro) for hay fever and as eye drops (Optivar) for allergic conjunctivitis.

Pharmacodynamics

Pharmacokinetics

Azelastine blocks histamine H1-receptor activity and inhibits release of inflammatory mediators from mast cells.

Absorption
40% absorbed sytemically through the nasal mucosa (intranasal).

Metabolism
Hepatic.

Excretion
Via faeces.

Azelastine Indications / Azelastine Uses

Information Not Available

Azelastine Adverse Reactions / Azelastine Side Effects

Irritation, stinging and itching of the nasal mucosa. Sneezing, nosebleeds, headache; nausea, taste disturbances, somnolence, dry mouth.

Precautions

Information Not Available

Special Precautions

Pregnancy, lactation. Tip of the bottle should be dipped in boiling water, dried and capped appropriately after every use.

Other Drug Interactions

Additive effects with CNS depressants and ethanol

Other Interactions

Information Not Available

Dosage

Ophthalmic
Conjunctivitis
Adult: Instill 1-2 drops of 0.05% solution into the affected eye/s bid, may increase to four times daily in severe cases.
Child: ≥4 yr: Instill 1-2 drops of 0.05% solution into the affected eye/s bid, may increase to four times daily in severe cases.

Nasal
Rhinitis
Adult: 140 mcg by nasal spray into each nostril bid.
Child: ≥5 yr: 140 mcg by nasal spray into each nostril bid.

Food(before/after)

Information Not Available

List of Contraindications

Azelastine and Pregnancy

Caution when used during pregnancy


Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.

Azelastine and Lactation

Caution when used during lactation

Azelastine and Children

Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of azelastine in children under the age of 3 years with use in other age groups.

Azelastine and Geriatic

This medicine has been tested and has not been shown to cause different side effects or problems in older people than it does in younger adults.

Azelastine and Other Contraindications

Hypersensitivity

Storage

Nasal
Store at 20-25°C.

Ophthalmic
Store at 2-25°C

Lab interference

Nasal
Store at 20-25°C.

Ophthalmic
Store at 2-25°C

© 2011-2022 DrugsUpdate.com. Disclaimer | Site Map

Feedback
  • Companies that own platforms will own the market
  • Trusted and recognized by all Doctors
  • Access to Millions of Visitors instantly.
  • Companies that own platforms will own the market
  • Trusted and recognized by all Doctors
  • Access to Millions of Visitors instantly.