Bambuterol Hydrochloride information from DrugsUpdate
P - Caution when used during pregnancy
Information Not Available
Pharmacodynamics
Pharmacokinetics
Bambuterol HCl is a prodrug of terbutaline. It relaxes bronchial smooth muscle by selectively acting on β2-receptors. Duration 24 hours
Absorption Absorbed from the GI tract following oral admin.
Metabolism Converted to active metabolite, terbutaline, at a slow rate of 4-7 hours.
Bambuterol Hydrochloride Indications / Bambuterol Hydrochloride Uses
Information Not Available
Bambuterol Hydrochloride Adverse Reactions / Bambuterol Hydrochloride Side Effects
Fine tremor of skeletal muscle (e.g. hands), palpitations and muscle cramps; tachycardia, tenseness and peripheral vasodilation.
Precautions
Information Not Available
Special Precautions
DM, hyperthyroidism, myocardial insufficiency, arrhythmias, susceptibility to QT-interval prolongation. Pregnancy.
Other Drug Interactions
Risk of hypokalaemia increased by co-admin of corticosteroids, diuretics or xanthines. Prolong the action of drugs e.g. suxamethonium.
Other Interactions
Information Not Available
Dosage
Oral Persistent reversible airways obstruction Adult: 10-20 mg once daily at bedtime. CrCl (ml/min):<50 Dosage Recommendation: Initial dose should be halved.
Food(before/after)
May be taken with or without food. (Preferably taken shortly before bedtime.)
List of Contraindications
Bambuterol Hydrochloride and Pregnancy
Caution when used during pregnancy
Bambuterol Hydrochloride and Lactation
Information Not Available
Bambuterol Hydrochloride and Children
Information Not Available
Bambuterol Hydrochloride and Geriatic
Information Not Available
Bambuterol Hydrochloride and Other Contraindications
Severe hepatic impairment; cirrhosis
Storage
Oral: Store below 30 ℃
Lab interference
Oral: Store below 30 ℃
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