Ambroxol information from DrugsUpdate
P - Caution when used during pregnancy.
Ambroxol is a clinically proven systemically active mucolytic agent. When administered orally onset of action occurs after about 30 minutes. The breakdown of acid mucopolysaccharide fibers makes the sputum thinner and less viscous and therefore more easily removed by coughing. Although sputum volume eventually decreases, its viscosity remains low for as long as treatment is maintained.
Pharmacodynamics
Pharmacokinetics
Alteplase initiates local fibrinolysis and dissolution of clots by binding to fibrin in a thrombus and the fibrin-bound plasminogen is converted to plasmin.
Excretion
Cleared rapidly from the plasma mainly by hepatic metabolism. Half-life: 4-5 minutes (initial); about 40 minutes (terminal).
Ambroxol Indications / Ambroxol Uses
Information Not Available
Ambroxol Adverse Reactions / Ambroxol Side Effects
Mind GI effects & allergic reactions
Precautions
Information Not Available
Special Precautions
Information Not Available
Other Drug Interactions
Information Not Available
Other Interactions
Information Not Available
Dosage
Oral
Mucolytic: Adult- 60-120mg daily in two-three divided doses. Child- <2 years: 7.5 mg bid; 2-5 years 7.5 mg bid/tid; 6-12 years: 15mg bid/tid.
Food(before/after)
Information Not Available
List of Contraindications
Ambroxol and Pregnancy
Caution when used during pregnancy.
Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.
Ambroxol and Lactation
Information Not Available
Ambroxol and Children
Information Not Available
Ambroxol and Geriatic
Information Not Available
Ambroxol and Other Contraindications
There are no absolute contraindications but in patients with gastric ulceration relative caution should be observed.
Storage
Store at a temperature not exceeding 30 degrees celsius
Lab interference
Store at a temperature not exceeding 30 degrees celsius
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