Eicosapentaenoic acid information from DrugsUpdate
Eicosapentaenoic acid, an essential fatty acid, is indicated for the treatment and management of depression, borderline personality disorders and symptoms of postmenopausal symptoms including hot flashes. Eicosapentaenoic acid is also indicated for wound healing and to reduce the risk of stroke, heart attack and thrombosis.
Pharmacodynamics
Eicosapentaenoic acid can prevent blood clotting and symptoms of inflammation including edema and pain.
Pharmacokinetics
No information available
Eicosapentaenoic acid Indications / Eicosapentaenoic acid Uses
No information available
Eicosapentaenoic acid Adverse Reactions / Eicosapentaenoic acid Side Effects
In recommended doses, Eicosapentaenoic acid is likely safe. However, Eicosapentaenoic acid may cause diarrhoea, nausea, skin rashes, epistaxis, belching and heartburn in some patients.
Precautions
Eicosapentaenoic acid is contraindicated in patients with aspirin-sensitivity and patients on anti-hypertensive therapy.
Special Precautions
No information available
Other Drug Interactions
Eicosapentaenoic acid may interact with anti-hypertensive drugs, anticoagulants, anti-platelet drugs, calcium-channel blockers, anticoagulants, aspirin, clopidogrel and NSAIDs.
Other Interactions
No information available
Dosage
Eicosapentaenoic acid is generally prescribed with docosahexaenoic acid. The recommended dosage of Eicosapentaenoic acid is 563 mg.
For treatment of depression (Adults):
One gram of EPA, twice dailyFor treatment of borderline personality disorder (Adults):
One gram of EPA, up to eight weeks.
For treatment of postmenopausal symptoms:
Consider administration of 500 mg of ethyl-EPA, thrice daily for 8 weeks.
Food(before/after)
No information available
List of Contraindications
Eicosapentaenoic acid and Pregnancy
Not classified under USFDA Pregnancy Category. In recommended doses, Eicosapentaenoic acid is likely safe among pregnant women.
Eicosapentaenoic acid and Lactation
In recommended doses, Eicosapentaenoic acid is likely safe among lactating mothers. Nursing mothers should consult a physician before taking Eicosapentaenoic acid.
Eicosapentaenoic acid and Children
Eicosapentaenoic acid should not be used in children unless prescribed by a pediatrician
Eicosapentaenoic acid and Geriatic
No information available
Eicosapentaenoic acid and Other Contraindications
No information available
Storage
No information available
Lab interference
No information available
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