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Quinapril hydrochloride information from DrugsUpdate  

See Available Brands of Quinapril hydrochloride in India

Quinapril hydrochloride, an anti-hypertensive drug, is prescribed for the treatment of hypertension and heart failure in adults. Quinapril hydrochloride can be given either as a monotherapy or a combined therapy with digitalis or diuretics.

Pharmacodynamics

No information available

Pharmacokinetics

No information available

Quinapril hydrochloride Indications / Quinapril hydrochloride Uses

No information available

Quinapril hydrochloride Adverse Reactions / Quinapril hydrochloride Side Effects

Quinapril hydrochloride can cause back pain, fatigue, chest pain, headache, diarrhoea, dyspnoea, myalgia, rashes, abdominal pain, coughing, dizziness, rash, hypotension, coughing and nausea or vomiting.

Precautions

Quinapril hydrochloride is contraindicated in patients with serious anaphylactoid reactions, head and neck angioedema, intestinal angioedema, desensitization-related and membrane exposure associated anaphylactoid reactions, hypotension, hepatic failure and neutropenia or agranulocytosis.

Special Precautions

No information available

Other Drug Interactions

Quinapril hydrochloride may interact with potassium supplements, potassium-sparing diuretics, other diuretics, lithium, tetracycline, COX-2 inhibitors and gold salts.

Other Interactions

No information available

Dosage

For the treatment of hypertension (Adults):
As a monotherapy, consider an initial daily dose of 10-20 mg of Quinapril hydrochloride. The dosage can be adjusted in accordance with the requirement. The dosage can be increased up to 80 mg/day in divided doses.
 
As a concomitant therapy with diuretics (Adults):
Start with an initial dose of 5 mg. After three days of therapy, the diuretics should be stopped.
 
For treatment of heart failure (Adults):
As an adjunctive therapy with diuretics or digitalis, consider administration of 5 mg of Quinapril hydrochloride, twice daily. The dosage can be increased up to 20-40 mg in two divided doses. The treatment should be initialized under close medical supervision to prevent azotemia, hypotension and orthostasis.

Food(before/after)

Quinapril hydrochloride can be taken before or after food intake

List of Contraindications

Quinapril hydrochloride and Pregnancy

Contraindicated in pregnancy
USFDA pregnancy category D. Quinapril hydrochloride can harm the unborn fetus. Perform pregnancy tests before using Quinapril hydrochloride. Use effective contraceptive mode to prevent unintended pregnancies while taking Quinapril hydrochloride.

Quinapril hydrochloride and Lactation

Nursing mothers should consult the healthcare provider before Quinapril hydrochloride treatment.

Quinapril hydrochloride and Children

No information available

Quinapril hydrochloride and Geriatic

No information available

Quinapril hydrochloride and Other Contraindications

No information available

Storage

No information available

Lab interference

No information available

Quinapril hydrochloride brands in India:

Acupil Acupil-H Q-Pril Q-Pril-H

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