Adefovir dipivoxil information from DrugsUpdate
Adefovir dipivoxil, a nucleotide analogue, is indicated for the treatment of hepatitis B infection in individuals 12 years of age and over. Adefovir dipivoxil is a viral suppressant. However, the drug cannot cure and prevent the transmission of hepatitis B.
Pharmacodynamics
No information available
Pharmacokinetics
No information available
Adefovir dipivoxil Indications / Adefovir dipivoxil Uses
No information available
Adefovir dipivoxil Adverse Reactions / Adefovir dipivoxil Side Effects
Adefovir dipivoxil can cause hypersensitivity, diarrhoea, fatigue, fever, nausea, vomiting, increased cough, metabolic acidosis, shallow breathing, myalgia, drowsiness and dizziness.
Precautions
Do not stop taking Adefovir dipivoxil unless advised by a physician. It can cause worsening of symptoms and fatal results. Adefovir dipivoxil is contraindicated in renal disorder patients, HIV/AIDS patients, liver transplanted patients and obese individuals.
Special Precautions
No information available
Other Drug Interactions
Adefovir dipivoxil may interact with aminoglycosides, tenofovir, tacrolimus, NSAIDs, vancomycin, cyclosporine and amphotericin-B.
Other Interactions
No information available
Dosage
For treatment of chronic Hepatitis B:
Start with an oral initial dose of 10 mg, once daily. The treatment can be continued or discontinued based on therapeutic response.
Food(before/after)
Can be taken before or after food intake
List of Contraindications
Adefovir dipivoxil and Pregnancy
USFDA pregnancy category C. May be or may not be harmful to an unborn baby. Consult your doctor if you are in gestation or planning to have a baby during Adefovir dipivoxil treatment.
Adefovir dipivoxil and Lactation
It is not known whether Adefovir dipivoxil can pass through the breast milk or not. Nursing mothers should avoid breastfeeding while taking Adefovir dipivoxil.
Adefovir dipivoxil and Children
Adefovir dipivoxil is not recommended for children less than 12 years of age.
Adefovir dipivoxil and Geriatic
No information available
Adefovir dipivoxil and Other Contraindications
No information available
Storage
No information available
Lab interference
No information available
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