Ofloxacin + Ornidazole information from DrugsUpdate
Ofloxacin + Ornidazole, a combined formulation of antibiotics, are prescribed for the treatment of peridonitis, diarrhoea, dysentery, gingivitis and pelvic inflammatory disease.
Pharmacodynamics
Ornidazole:
Ornidazole reduce the nitro group to more reactive amine groups that interrupt with the formation of microbial DNA. The action of Ornidazole results in loss of helical structure and DNA breakdown.
Ofloxacin:
Ofloxacin inhibits the formation of bacterial DNA gyrase. Ofloxacin is effective against Mycobacterium species including M. leprae, M. tuberculosis and Chlamydia trachomatis.
Pharmacokinetics
No information available
Ofloxacin + Ornidazole Indications / Ofloxacin + Ornidazole Uses
No information available
Ofloxacin + Ornidazole Adverse Reactions / Ofloxacin + Ornidazole Side Effects
Ofloxacin + Ornidazole can cause vaginitis, tendon damage, anaphylactic reactions, nausea or vomiting, abdominal pain, hallucinations, diarrhoea, dizziness, insomnia and photosensitivity.
Precautions
Ofloxacin + Ornidazole is contraindicated in patients with blood dyscrasias, neurological disorders, hepatic disorders, suspected CNS disorders,
Special Precautions
No information available
Other Drug Interactions
Ofloxacin + Ornidazole may interact with acenocoumarol, anisindione, calcium salts including calcium acetate, NSAIDs, antacids, hematinics and muscle relaxants such as vecuronium bromide.
Other Interactions
Do not consume alcohol while taking Ofloxacin + Ornidazole
Dosage
The dosage and duration should be as prescribed by a physician
Food(before/after)
Ofloxacin + Ornidazole can be taken before or after food intake
List of Contraindications
Ofloxacin + Ornidazole and Pregnancy
USFDA pregnancy category C. May be or may not be harmful to an unborn baby. Consult your doctor if you are in gestation or plan to have a baby during Ofloxacin + Ornidazole treatment.
Ofloxacin + Ornidazole and Lactation
It is not known whether Ofloxacin + Ornidazole can pass through the breast milk or not. Nursing mothers should avoid breastfeeding while taking Ofloxacin + Ornidazole.
Ofloxacin + Ornidazole and Children
The dosage and duration should be as prescribed by a physician
Ofloxacin + Ornidazole and Geriatic
No information available
Ofloxacin + Ornidazole and Other Contraindications
No information available
Storage
No information available
Lab interference
No information available
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