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Butriptyline information from DrugsUpdate  

See Available Brands of Butriptyline in India

Butriptyline, a class of non-selective monoamine reuptake inhibitors, is indicated for the treatment and management of depression.

Pharmacodynamics

Similar to Amitriptyline, Butriptyline possesses the anti-depressant property by inhibition of neuronal re-uptake of serotonin and norepinephrine. The tricyclic anti-depressant drug exerts weak sedating property.

Pharmacokinetics

No information available

Butriptyline Indications / Butriptyline Uses

No information available

Butriptyline Adverse Reactions / Butriptyline Side Effects

Butriptyline can cause galactorrhoea, hypersensitivity reactions, behavioural changes, sexual dysfunctions, cardiovascular effects, tremors, nausea, sweating, testicular enlargement, dyskinesia, fever, seizures, movement disorders, hyperglycemia, bulimia and blood dyscrasia.

Precautions

Butriptyline is contraindicated in patients with porphyria, severe hepatic disorders, behavioural disorders, recent history of MI and CVD, seizures, close-angle glaucoma, urinary retention, diabetes, concurrent electroconvulsive therapy, pheochromocytoma and thyroid dysfunctions. Do not withdraw Butriptyline treatment abruptly. Butriptyline may impair thinking and alertness. Do not drive vehicles or operate heavy machinery while taking Butriptyline.

Special Precautions

No information available

Other Drug Interactions

Butriptyline may interact with verapamil, disulfiram, diltiazem, cimetidine, adrenaline, amiodarone, SSRIs, thioridazine, propafenone, baclofen, sotalol, MAOIs, noradrenaline, sibutramine, estrogen, nitrates, carbamazepine, terfenadine, clonidine, procainamide, pimozide, opioid analgesics, sedatives, anti-muscarinics and anxiolytics.

Other Interactions

Do not consume alcohol while taking Butriptyline. It can cause serious adverse events.
Food (Before/After)
Butriptyline can be taken before or after food intake

Dosage

For depression (Adults):
Start with an initial dose of 25 mg of Butriptyline thrice daily. The maximum daily dose should not exceed 150 mg/day.

Food(before/after)

No information available

List of Contraindications

Butriptyline and Pregnancy

USFDA pregnancy category C. May be or may not be harmful to an unborn baby. Consult a physician if you are in gestation or planning to have a baby during Butriptyline treatment.

Butriptyline and Lactation

Nursing should avoid breastfeeding while taking Butriptyline.

Butriptyline and Children

No information available

Butriptyline and Geriatic

No information available

Butriptyline and Other Contraindications

No information available

Storage

No information available

Lab interference

No information available

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