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Botulinum toxin type A information from DrugsUpdate  

See Available Brands of Botulinum toxin type A in India

Botulinum toxin type A, also called as Onabotulinumtoxin A, is indicated for the treatment of cervical dystonia, hyperhidrosis, overactive bladder, eyelid spasms and moderate form of muscular spasms in hands and arms. Botulinum toxin type A is also prescribed for the prophylaxis of chronic migraine headache in adults with recurrence. In cosmetic medicine, Botulinum toxin type A is used to reduce the facial wrinkles. However, the effects are temporary.

Pharmacodynamics

Botulinum toxin type A blocks the neuromuscular transmission on motor and/or sympathetic nerve terminals by inhibition of acetylcholine release. Intramuscular injection of Botulinum toxin type A results in chemical denervation of muscles with reduction of muscular activity. Botulinum toxin type A can cause temporary denervation of sweat glands and reduce the formation of sweats.

Pharmacokinetics

No information available

Botulinum toxin type A Indications / Botulinum toxin type A Uses

No information available

Botulinum toxin type A Adverse Reactions / Botulinum toxin type A Side Effects

Botulinum toxin type A can cause chest pain, urinary incontinence, unusual muscle weakness, drooping eyelids, troubled speech or breathing, paced heartbeats, eye discharge, vision changes, bruising tendencies, watery eyes, headache, drowsiness, nausea, diarrhoea, anorexia, injection-site reactions, flu-like symptoms, bruising, photosensitivity and dry mouth.

Precautions

Botulinum toxin type A is contraindicated in patients with bleeding disorders, facial weakness, myasthenia gravis, ALS, asthma or emphysema, heart disorders, convulsions and other muscular disorders. Botulinum toxin type A should not be used if you had or need to undergo facial surgery. Botulinum toxin type A should not be used within four months of previous shots.
Botulinum toxin type A can cause vision changes. Do not drive vehicle or operate heavy machineries within 48 hours of Botulinum toxin type A administration.

Special Precautions

No information available

Other Drug Interactions

Botulinum toxin type A may interact with diuretics, muscle relaxants, sedatives, bronchodilators, irritable bowel syndrome medicines, anti-histamines and hypnotics.

Other Interactions

Avoid using deodorants or antiperspirants within 24hours of Botulinum toxin type A administration. Avoid outdoor activities or sports for two days after Botulinum toxin type A treatment.

Dosage

No information available

Food(before/after)

No information available

List of Contraindications

Botulinum toxin type A and Pregnancy

USFDA Pregnancy Category C. It is not known whether Botulinum toxin type A will harm an unborn baby. Consult a healthcare provider if you are pregnant or plan to become pregnant while using this medication.
Botulinum toxin A and Lactation
It is not known whether Botulinum toxin type A passes into the breast milk or not. Nursing mothers should consult a doctor before receiving Botulinum toxin type A.

Botulinum toxin type A and Lactation

No information available

Botulinum toxin type A and Children

No information available

Botulinum toxin type A and Geriatic

No information available

Botulinum toxin type A and Other Contraindications

No information available

Storage

No information available

Lab interference

No information available

Botulinum toxin type A brands in India:

Botox Neuronox

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