Barnidipine information from DrugsUpdate
Barnidipine, a calcium-channel blocker, is prescribed for the management of hypertension in adults. Barnidipine is a selective calcium-channel blockers belong to dihydropyridine analogues. The mechanism of action of Barnidipine is mostly vascular effects.
Pharmacodynamics
Barnidipine is a peripheral and coronary vasodilator with no effects on cardiac conduction. The drug exerts vasodilatation with reduced peripheral resistance, after load and blood pressure with increased heart rate, coronary blood flow, oxygen supply and cardiac output.
Pharmacokinetics
No information available
Barnidipine Indications / Barnidipine Uses
No information available
Barnidipine Adverse Reactions / Barnidipine Side Effects
Barnidipine can cause gingival hyperplasia, impotence, headache, hypotension, increased micturition, ischemic chest pain, GI disturbances, tremors, dizziness, flushing, cerebral or myocardial ischemia, transient blindness, lethargy, eye pain and impotence.
Precautions
Barnidipine is contraindicated in patients with poor cardiac reserve, aortic stenosis, heart failure, cardiogenic shock, recent history of unstable angina or MI, aortic stenosis and hypotension. Do not stop Barnidipine treatment abruptly.
Special Precautions
No information available
Other Drug Interactions
Barnidipine may interact with erythromycin, rifampicin, aldesleukin, antihypertensive drugs, quinidine, phenytoin, rifampicin, erythromycin, carbamazepine, anti-psychotics and cimetidine.
Other Interactions
Do not consume grapefruit, grape wine, grape fruit juice while taking Barnidipine.
Dosage
For hypertension (Adults):
Start with an initial dose of 5-10 mg of Barnidipine once daily. The dosage can be increased based on the clinical response. The maintenance dose of Barnidipine is 10-20 mg, once daily.
Food(before/after)
Barnidipine can be taken before or after food intake
List of Contraindications
Barnidipine and Pregnancy
Contraindicated in pregnancy
USFDA pregnancy category X. Barnidipine can harm the unborn fetus. Perform pregnancy tests before using Barnidipine. Use effective contraceptive mode to prevent unintended pregnancies while taking Barnidipine.
Barnidipine and Lactation
Nursing mothers should consult the healthcare provider before Barnidipine treatment.
Barnidipine and Children
No information available
Barnidipine and Geriatic
No information available
Barnidipine and Other Contraindications
No information available
Storage
No information available
Lab interference
No information available
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