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Barnidipine information from DrugsUpdate  

See Available Brands of Barnidipine in India

Barnidipine, a calcium-channel blocker, is prescribed for the management of hypertension in adults. Barnidipine is a selective calcium-channel blockers belong to dihydropyridine analogues. The mechanism of action of Barnidipine is mostly vascular effects.

Pharmacodynamics

Barnidipine is a peripheral and coronary vasodilator with no effects on cardiac conduction. The drug exerts vasodilatation with reduced peripheral resistance, after load and blood pressure with increased heart rate, coronary blood flow, oxygen supply and cardiac output.

Pharmacokinetics

No information available

Barnidipine Indications / Barnidipine Uses

No information available

Barnidipine Adverse Reactions / Barnidipine Side Effects

Barnidipine can cause gingival hyperplasia, impotence, headache, hypotension, increased micturition, ischemic chest pain, GI disturbances, tremors, dizziness, flushing, cerebral or myocardial ischemia, transient blindness, lethargy, eye pain and impotence.

Precautions

Barnidipine is contraindicated in patients with poor cardiac reserve, aortic stenosis, heart failure, cardiogenic shock, recent history of unstable angina or MI, aortic stenosis and hypotension. Do not stop Barnidipine treatment abruptly.

Special Precautions

No information available

Other Drug Interactions

Barnidipine may interact with erythromycin, rifampicin, aldesleukin, antihypertensive drugs, quinidine, phenytoin, rifampicin, erythromycin, carbamazepine, anti-psychotics and cimetidine.

Other Interactions

Do not consume grapefruit, grape wine, grape fruit juice while taking Barnidipine.

Dosage

For hypertension (Adults):
Start with an initial dose of 5-10 mg of Barnidipine once daily. The dosage can be increased based on the clinical response. The maintenance dose of Barnidipine is 10-20 mg, once daily.

Food(before/after)

Barnidipine can be taken before or after food intake

List of Contraindications

Barnidipine and Pregnancy

Contraindicated in pregnancy


USFDA pregnancy category X. Barnidipine can harm the unborn fetus. Perform pregnancy tests before using Barnidipine. Use effective contraceptive mode to prevent unintended pregnancies while taking Barnidipine.

Barnidipine and Lactation

Nursing mothers should consult the healthcare provider before Barnidipine treatment.

Barnidipine and Children


No information available

Barnidipine and Geriatic


No information available

Barnidipine and Other Contraindications

No information available

Storage

No information available

Lab interference

No information available

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