Bromelain information from DrugsUpdate
Bromelain, a naturally occurring phytoenzyme is present in pineapple and pineapple juice. Bromelain is generally prescribed for the treatment of osteoarthritis, inflammation, hay fever, ulcerative colitis, debridement and shortening of labor. Bromelain can help muscle relaxation, improve antibiotic absorption and prevent cancer.
Bromelain is generally available as Bromelain with trypsin and rutin formulations.
Pharmacodynamics
Bromelain reduces inflammation by interfering with the enzymatic synthesis involved in Arachidonic acid metabolic pathway. Inhibition of such enzymes results in increased bleeding time and prevention or reduced inflammation. Bromelain can interfere with growth of malignant cells by unknown mechanisms.
Pharmacokinetics
No information available
Bromelain Indications / Bromelain Uses
No information available
Bromelain Adverse Reactions / Bromelain Side Effects
Bromelain can cause bleeding tendency, easy bruising and increased clotting time. In certain cases, Bromelain can cause diarrhoea and other GI discomfort.
Precautions
Bromelain is contraindicated in patients who are allergic to pineapple, carrot, fennel, grass pollen, cypress pollen, celery and synthetic Bromelain products/supplements. Bromelain should not be given to patients who need to undergo surgery within two weeks. Stop taking Bromelain at least two weeks prior to a scheduled surgery to avoid bleeding risks.
Special Precautions
No information available
Other Drug Interactions
Bromelain may interact with amoxicillin, tetracycline group of antibiotics, anticoagulants, anti-platelet drugs including NSAIDs.
Other Interactions
As a phytoproduct, Bromelain may interact with angelica, aniseed, ginger, asafoetida, celery, chamomile, alfalfa, fenugreek, willow, red clover, licorice, chestnut, poplar, quassia, zinc, potato and soybean.
Dosage
For Osteoarthritis (Adults):
Consider administration of 2 tablets, thrice daily.
Food(before/after)
Bromelain can be taken before or after food intake
List of Contraindications
Bromelain and Pregnancy
No information available
Bromelain and Lactation
It is not known whether Bromelain can pass through the breast milk or not. Breastfeeding mothers should avoid nursing while taking Bromelain.
Bromelain and Children
No information available
Bromelain and Geriatic
No information available
Bromelain and Other Contraindications
Information not available
Storage
Store below 25°C. Protect from light.
Lab interference
Store below 25°C. Protect from light.
FOLLOW US:
