Sitagliptin information from DrugsUpdate
Sitagliptin phosphate, an oral anti-diabetic drug, is prescribed for the treatment and management of type-2 diabetes mellitus in adults. The drug is either prescribed as a monotherapy or as a combined therapy with other anti-diabetic drugs. Sitagliptin phosphate lowers plasma glucose levels and regulates blood glucose and insulin levels. However, Sitagliptin phosphate is not indicated for type-1 diabetic patients.
Pharmacodynamics
No information available
Pharmacokinetics
No information available
Sitagliptin Indications / Sitagliptin Uses
No information available
Sitagliptin Adverse Reactions / Sitagliptin Side Effects
Sitagliptin phosphate can cause serious pancreatitis, changes in urination, severe skin reaction, runny nose, sore throat, headache, nausea, diarrhoea or constipation, myalgia, arthralgia and paced heart beats.
Precautions
Sitagliptin phosphate is contraindicated in patients with clinical history of pancreatitis and in dialysis-dependent renal patients.
Special Precautions
No information available
Other Drug Interactions
Sitagliptin phosphate may interact with insulin, oral anti-diabetic drugs, Probenecid, NSAIDs, aspirin, blood thinners, sulfa drugs, MAOIs and beta-blockers.
Other Interactions
No information available
Dosage
For Diabetes Type 2 (Adults):
Consider oral administration of 100 mg of Sitagliptin phosphate, once daily
Food(before/after)
Sitagliptin phosphate can be taken before or after food intake
List of Contraindications
Sitagliptin and Pregnancy
USFDA pregnancy category B. Sitagliptin phosphate may not cause harm to an unborn foetus. Before Sitagliptin phosphate treatment, the patient should discuss with the physician, if they are planning for a pregnancy.
Sitagliptin and Lactation
It is unclear whether the drug could pass through the breast milk to a breast feeding a baby. Consult your physician before taking Sitagliptin phosphate, if you are nursing mother.
Sitagliptin and Children
Sitagliptin phosphate should not be given to children younger than 18 years old without a Paediatrician’s advice.
Sitagliptin and Geriatic
No specific information
Sitagliptin and Other Contraindications
No specific information
Storage
Store at 20-25°C.
Lab interference
Store at 20-25°C.
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