logo image

Salmeterol information from DrugsUpdate  

See Available Brands of Salmeterol in India

P - Caution when used during pregnancy

Salmeterol is a long-acting beta2-adrenergic receptor agonist drug that is currently prescribed for the treatment of asthma and chronic obstructive pulmonary disease (COPD). It is currently available as a metered-dose inhaler (MDI) or a proprietary "disk-styled" inhaler that releases a powdered form of the drug.



Salmeterol is a direct-acting sympathomimetic which relaxes bronchial smooth muscle by its selective action on β2 receptors with little effect on heart rate.

Oral inhalation: 10-20 minutes.

12 hours.

Plasma concentrations are negligible after inhalation.

About 96% bound to plasma proteins.

Hepatically hydroxylated.

About 25% and 60% of the dose was eliminated in the urine and faeces respectively, over a period of 7 days.

Salmeterol Indications / Salmeterol Uses

Information Not Available

Salmeterol Adverse Reactions / Salmeterol Side Effects

Fine skeletal muscle tremor especially hands, tachycardia, palpitations, muscle cramps, headache, paradoxical bronchospasm, angioedema, urticaria, hypotension and collapse.


When added to usual asthma therapy, there may be an increase in asthma-related deaths. Only use salmeterol as additional therapy for patient not adequately controlled on other asthma-controller medications (eg, low- to medium-dose inhaled corticosteroids) or whose disease severity clearly warrants initiation of treatment with 2 maintenance therapies, including salmeterol.

Monitor for signs of worsening asthma.


May result in exaggeration of adverse effects e.g. tachycardia and arrhythmia.

Special Precautions

Pregnancy. Arrhythmias, hyperthyroidism, hypertension, DM, myocardial insufficiency, susceptibility to QT-interval prolongation. May cause paradoxical bronchospasm. Not to be used for treatment of acute bronchospasm or patients with deteriorating asthma. Monitor serum potassium concentrations in severe asthma.

Other Drug Interactions

Diuretics, corticosteroids and xanthines may augment hypokalaemia. Risk of severe hypertension when used with MAOIs, TCAs and other sympathomimetics. Increased susceptibility to cardiac arrhythmias caused by digoxin and other cardiac glycosides.

Other Interactions

Information Not Available


Chronic asthma, Chronic obstructive pulmonary disease
Adult: As metered-dose aerosol: 2 inhalations of 25 mcg bid up to 100 mcg bid. As dry powder inhalation: 50 mcg bid or 100 mcg bid if necessary.
Child: As metered-dose aerosol: ≥4 yr: 50 mcg bid.


Information Not Available

List of Contraindications

Salmeterol and Pregnancy

Caution when used during pregnancy.

Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.

Salmeterol and Lactation

Information Not Available

Salmeterol and Children

Information Not Available

Salmeterol and Geriatic

Information Not Available

Salmeterol and Other Contraindications

Information Not Available


Store at 20-25°C.

Lab interference

Store at 20-25°C.

Salmeterol brands in India:

Azrol Salmeter Salvent Serobid

© 2011-2021 DrugsUpdate.com from UPilot INC. Disclaimer | Site Map

  • Companies that own platforms will own the market
  • Trusted and recognized by all Doctors
  • Access to millions of Visitors instantly.
  • Companies that own platforms will own the market
  • Trusted and recognized by all Doctors
  • Access to millions of Visitors instantly.