Papaverine information from DrugsUpdate
Papaverine, a vasodilator, is prescribed for the treatment of intestinal and urine tract spasms. Papaverine relaxes blood vessels and facilitates blood flow in the spasmodic smooth muscles.
Pharmacodynamics
Papaverine exerts direct action on smooth muscles and cardiac muscles and alleviates spasms. However, the drug action is unrelated to muscle innervation. Anti-spasmodic activity of Papaverine relaxes smooth muscles of the pulmonary, coronary and systemic peripheries. Papaverine can lower cerebral vascular resistance and augments cerebral and cardiac hemodynamics.
Pharmacokinetics
No information available
Papaverine Indications / Papaverine Uses
No information available
Papaverine Adverse Reactions / Papaverine Side Effects
Discontinue Papaverine and consult a physician if symptoms of jaundice develop. Some of the other adverse events of Papaverine are arrhythmia, sweating, dizziness, anorexia, constipation, rashes, headache and flushing.
Precautions
Papaverine is contraindicated in patients with Parkinsonism, glaucoma, heart diseases and hepatic diseases. Do not operate heavy machinery or drive vehicles while taking Papaverine. Avoid getting up fast from bed after sleep to avoid falling.
Special Precautions
Information not available
Other Drug Interactions
Papaverine should not be concomitantly with Levodopa and other similar drugs.
Other Interactions
Do not consume alcohol while taking Papaverine. It may cause serious adverse events.
Dosage
Consider administration one capsule every 12 hours. In drug-unresponsive cases, the dose can be increased to one capsule every eight hours or two capsules every 12 hours.
Food(before/after)
Information not available
List of Contraindications
Papaverine and Pregnancy
FDA pregnancy category C. May be or may not be harmful to an unborn baby. Consult your doctor if you are in gestation or planning to have a baby.
Papaverine and Lactation
Nursing mothers should consult the healthcare provider before Papaverine treatment.
Papaverine and Children
Information not available
Papaverine and Geriatic
Information not available
Papaverine and Other Contraindications
Information not available
Storage
Store at 20-25°C.
Lab interference
Store at 20-25°C.
FOLLOW US:
