According to a recent study conducted by the University of Maryland, omega-3 fatty acid supplementation may improve symptoms of meibomian gland dysfunction. Previously published studies have shown that omega-3 fatty acids may attenuate symptoms of dry eye by increasing tear secretion.
The study found level-1 evidence and was strong. The size of the study was statistically significant, said Dr. Arun Jain, one of the researchers at the Postgraduate Institute of Medical Education and Research, Chandigarh.
The study enrolled 60 subjects with moderate symptoms of dry eye syndrome and was not treated. About half of the subjects were asked to take two capsules of fish oil that contains 1.2 g of omega-3 fatty acids with eicosapentaenoic acid and docosahexaenoic acid, 720 mg and 480 mg, twice daily. Rest of the subjects was assigned to take 400 mg of vitamin E daily.
Before intervention, the scores of meibum quality, Schirmer’s test, tear breakup time and meibum expressibility scores were assessed and found to be similar in both groups. The researchers observed improvements in all parameters, except the Schirmer’s test was observed.
Further studies are to be conducted to assess the health benefits of nutrients in meimobian gland dysfunction, the authors noted.