Even high doses of fish oil supplements that are rich in omega-3 fatty acids do not reduce the risk of atrial fibrillation, according to AFFORD trial conducted by the Montreal Heart Institute. The study was published in the Journal of the American College of Cardiology.
Atrial fibrillation (AF) is a common type of cardiac arrhythmia in elderly individuals. Other risk factors such as high blood pressure, obesity, diabetes and other heart diseases increase the risk of AF.
According to Dr. Anil Nigam, Cardiologist at Montreal Heart Institute, fish oil has no beneficial role against atrial rhythmic disorder, particularly atrial fibrillation. To prevent heart disease and hypertension, diet rich in omega-3s with restricted saturated fats are often recommended. Such strategies and benefits of fish oils should be studied further, he added.
The present study involved 337 AF patients who were not treated with conventional anti-arrhythmic drugs. The patients were randomly assigned to receive either 4 gm of fish oil or a placebo, every day, for up to 16 months. Recurrence of AF was reported in 64.1% of fish oil treated patients, compared to 63.2% placebo receivers. No reduction of oxidative stress biomarkers or inflammation in treated group.
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