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Basiliximab information from DrugsUpdate  

See Available Brands of Basiliximab in India

P - Caution when used during pregnancy
L - Caution when used during Lactation

Basiliximab is a chimeric mouse-human monoclonal antibody to the α chain (CD25) of the IL-2 receptor of T cells.It is used to prevent rejection in organ transplantation, especially in kidney transplants. 


Basiliximab, a chimeric murine/human monoclonal antibody, blocks the α-chain of the interleukin-2 receptor complex on the surface of activated T-lymphocytes.



Duration: 36 days.

Excretion: Terminal half-life: 7 days (adult) and 9 days (children).


Basiliximab Indications / Basiliximab Uses

Prophylaxis of acute graft rejection in renal transplantation (Intravenous)

Basiliximab Adverse Reactions / Basiliximab Side Effects

Peripheral oedema, hypertension, atrial fibrillation; fever, headache, insomnia, pain; wound complication, acne; hypokalaemia, hyperglycaemia, hyperuricaemia, hypophosphataemia, hypercholesterolaemia; GI effects; UTI; anaemia; tremor; dyspnoea, infection. Rarely, hypersensitivity and anaphylactoid-type reactions.


Information Not Available

Special Precautions

Pregnancy and lactation. Re-exposure to a subsequent course of therapy of basiliximab

Other Drug Interactions

Immunosuppressives other than ciclosporin and corticosteroids may increase the potential for over-immunosuppression

Other Interactions

Information Not Available




Prophylaxis of acute graft rejection in renal transplantation

Adult: 20 mg dose given by IV bolus or infusion over 20-30 min within 2 hr prior to transplantation surgery. Repeat once 4 days later. Withhold 2nd dose if graft loss or severe hypersensitivity reaction occurs.

Child: <35 kg: 10 mg dose 2 hr before surgery, repeated once 4 days later; ≥35 kg: same as adult dosing. Withhold 2nd dose if graft loss or severe hypersensitivity reaction occurs.



Information Not Available

List of Contraindications

Basiliximab and Pregnancy

Category B: Either animal-reproduction studies have not demonstrated a foetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1st trimester (and there is no evidence of a risk in later trimesters).

Basiliximab and Lactation

Caution when used during lactation

Basiliximab and Children

Information Not Available

Basiliximab and Geriatic

Information Not Available

Basiliximab and Other Contraindications

Hypersensitivity to basiliximab and murine proteins


Information Not Available

Lab interference

Information Not Available

Basiliximab brands in India:


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