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Doxofylline information from DrugsUpdate  

See Available Brands of Doxofylline in India

P - Caution when used during pregnancy
L - Caution when used during lactation

Methylxanthines are phosphodiesterase inhibitors. Doxofylline is a new generation long acting oral methyxanthine derivative. Its mainly used for maintenance therapy in patients suffering with Asthma and Chronic Obstructive Pulmonary Disease (COPD)

Pharmacodynamics

Doxofylline is a theophylline derivative. Similarly, its mechanism of action is related to the inhibition of phosphodiesterase activities, resulting in bronchodilating effects.

Pharmacokinetics

Information Not Available

Doxofylline Indications / Doxofylline Uses

Information Not Available

Doxofylline Adverse Reactions / Doxofylline Side Effects

Doxofylline has a prolonged bronchodilator effects and unlike theophylline it has least adenosine interactions i.e., no CNS and CVS side effects. There is no sleep disturbances and no effects on gastric secretions with doxofylline. It is highly safe in smokers.

Precautions

Information Not Available

Special Precautions

Information Not Available

Other Drug Interactions

Information Not Available

Other Interactions

Information Not Available

Dosage

Adult: 400mg once a day. Single dose administration in the evening reduces nocturnal symptoms and helps to keep the patients complaint free during the day. However, in certain cases 400mg twice daily is recommended on the basis of the clinical response.

Food(before/after)

Information Not Available

List of Contraindications

Doxofylline and Pregnancy

Information Not Available

Doxofylline and Lactation

Information Not Available

Doxofylline and Children

Information Not Available

Doxofylline and Geriatic

Information Not Available

Doxofylline and Other Contraindications

Hypersensitivity to doxofulline and other methyxanthine derivatives. Methyxanthines are not recommended for therapy of asthma exacerbations.

Storage

Information Not Available

Lab interference

Information Not Available

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