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Paraffin information from DrugsUpdate  

See Available Brands of Paraffin in India

In chemistry, paraffin is a term that can be used synonymously with "alkane", indicating hydrocarbons with the general formula CnH2n+2. Paraffin wax refers to a mixture of alkanes that falls within the 20 ≤ n ≤ 40 range; they are found in the solid state at room temperature and begin to enter the liquid phase past approximately 37°C.

Pharmacodynamics

When taken orally: penetrates and softens faecal material. When used topically: softens and hydrates skin. When used in the eye: lubricates and protects eye.

Pharmacokinetics

Onset: When admin orally: produces laxation after 6-8 hr.

Paraffin Indications / Paraffin Uses

Information Not Available

Paraffin Adverse Reactions / Paraffin Side Effects

Anal irritation (excessive dose) and seepage. Foreign-body granulomatous reactions; vasospasm; lipoid pneumonia; interference with absorption of fat-soluble vitamins. When applied ophthalmically, may cause temporary visual disturbance.

Precautions

Information Not Available

Special Precautions

Oral: not recommended for use in patients with difficulty swallowing or impaired neurodevelopment. Avoid prolonged use as a laxative or faecal softener. Contact lens should not be worn at the same time (interval of at least 30 min). Ocular preparations should be applied at least 5 min after any other ocular medication.

Other Drug Interactions

May impair absorption of fat-soluble vitamins and possibly other compounds.

Other Interactions

Information Not Available

Dosage

Oral
Constipation
Adult: Up to 45 ml/day, usually in the evening but should not be taken immediately before going to bed. Max duration of treatment: 1 wk.
Child: 3-12 yr: 0.5-1 ml/kg (max 30 ml) once daily; 12-18 yr: 10-30 ml once daily, normally after evening meal but not immediately before going to bed. May be mixed with ice cream or yoghurt to increase palatability. Max duration of treatment: 1 wk.
Ophthalmic
Dry eye
Adult: Apply as required, usually at night.
Child: Apply as required, usually at night.
Rectal
Constipation
Adult: 120 ml (range 60-150 ml) daily as an enema.
Child: 2-11 yr: 30-60 ml daily as an enema.
Topical/Cutaneous
Hydrate and soften skin
Adult: Apply as required, especially after bath or shower.
Child: Apply as required, especially after bath or shower.

Food(before/after)

Information Not Available

List of Contraindications

Paraffin and Pregnancy

Information Not Available

Paraffin and Lactation

Information Not Available

Paraffin and Children

Information Not Available

Paraffin and Geriatic

Information Not Available

Paraffin and Other Contraindications

Abdominal pain, nausea and vomiting is present; children <3 yr.

Storage

Ophthalmic: Store <25°C. After opening ocular preparation, discard after 28 days. Topical/Cutaneous: For creams and ointments: store <25°C.

Lab interference

Ophthalmic: Store <25°C. After opening ocular preparation, discard after 28 days. Topical/Cutaneous: For creams and ointments: store <25°C.

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