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Norfloxacin + Tinidazole information from DrugsUpdate  

See Available Brands of Norfloxacin + Tinidazole in India

Norfloxacin; Belongs to the class of quinolones, fluoroquinolone. Used in the treatment of systemic infections.
Tinidazole; Belongs to the class of imidazole derivative antibacterials. Used in the treatment of systemic infections.
tinidazole; Belongs to the class of nitroimidazole derivatives antiprotozoals. Used in the treatment amoebiasis and other protozoal diseases.
norfloxacin; Belongs to the class of other antiinfectives. Used in the treatment of eye infections.

Pharmacodynamics

Tinidazole is active against protozoa and anaerobic bacterial infections against which norfloxacin is inactive. The combination of norfloxacin and tinidazole has an extended range of antimicrobial spectrum and is effective in mixed gut infections, diarrhoeas and dysentery.

Pharmacokinetics

Information Not Available

Norfloxacin + Tinidazole Indications / Norfloxacin + Tinidazole Uses

Information Not Available

Norfloxacin + Tinidazole Adverse Reactions / Norfloxacin + Tinidazole Side Effects

Nausea, vomiting, heartburn, metallic taste, headache, dizziness, depression, insomnia, rash, dry mouth, fever, arthralgia. Rarely eosinophilia, bone marrow depression.
Potentially Fatal: Rarely hypersensitivity reactions, facial and laryngeal oedema, hypotension, bronchospasm.

Special Precautions

Moderate renal impairment, history of or susceptibility to seizures, alcohol intake. Ensure adequate hydration and urine output.

Other Drug Interactions

Antacids reduce absorption of norfloxacin from gut. Probenecid reduces urinary excretion of norfloxacin.
Potentially Fatal: Increased levels of theophylline and ciclosporin, warfarin effects potentiated, disulfiram-like reactions with alcohol.

Other Interactions

Food interactions: Reduced absorption of norfloxacin esp with milk or yogurt.

Dosage

Oral
Diarrhoea and dysentery of amoebic, bacterial or mixed origins
Adult: Per tablet contains norfloxacin 400 mg and tinidazole 600 mg: 1 tablet bid for 5 days.

Food(before/after)

Information Not Available

List of Contraindications

Norfloxacin + Tinidazole and Pregnancy

Information Not Available

Norfloxacin + Tinidazole and Lactation

Information Not Available

Norfloxacin + Tinidazole and Children

Information Not Available

Norfloxacin + Tinidazole and Geriatic

Information Not Available

Norfloxacin + Tinidazole and Other Contraindications

Hypersensitivity, neurological disorders including convulsions, blood dyscrasias, children. Pregnancy and lactation.

Storage

Information Not Available

Lab interference

Information Not Available

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