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Dexibuprofen information from DrugsUpdate  

See Available Brands of Dexibuprofen in India

P - Contraindicated in pregnancy

Dexibuprofen is a non-steroidal anti-inflammatory drug. It is the d isomer of ibuprofen.

Pharmacodynamics

Pharmacokinetics

Dexibuprofen is a NSAID. It acts by inhibition of cyclo-oxygenase, which is involved in prostaglandin synthesis.

Dexibuprofen Indications / Dexibuprofen Uses

Information Not Available

Dexibuprofen Adverse Reactions / Dexibuprofen Side Effects

GI bleeding, heartburn, epigastric pain; dyspepsia, peptic ulcer; nausea, vomiting, diarrhoea; jaundice, hepatitis; rash; thrombocytopaenia; visual disturbances; tinnitus; depression; fatigue, headache, dizziness, vertigo.

Precautions

Information Not Available

Special Precautions

History of bronchial asthma; renal or hepatic disorders; bleeding disorders; CV disease; elderly; lactation.

Other Drug Interactions

Avoid concomitant use with anticoagulants, other NSAIDs and salicylates. Increases risk of methotrexate and lithium toxicity.

Other Interactions

Food Interactions:Decreased peak serum levels if taken with food but no effect on the extent of absorption.

Dosage

Oral
Pain and inflammation associated with musculoskeletal and joint disorders, Dysmenorrhoea
Adult: 600-900 mg daily in 2-3 divided doses. May increase to 1200 mg daily for patients with acute conditions or exacerbations.
Max Dosage: 400 mg/dose and 1200 mg/day.
Renal impairment: Dose reduction is recommended.
Hepatic impairment: Dose reduction is recommended.

Food(before/after)

Information Not Available

List of Contraindications

Dexibuprofen and Pregnancy

Contraindicated in pregnancy

Dexibuprofen and Lactation

Information Not Available

Dexibuprofen and Children

Information Not Available

Dexibuprofen and Geriatic

Information Not Available

Dexibuprofen and Other Contraindications

Hypersensitivity to aspirin or NSAIDs; active or suspected GI ulcer or history of recurrent GI ulcer; GI bleeding or other active bleedings or bleeding disorders; active Crohn's disease or ulcerative colitis; haemorrhagic diasthesis and other coagulation disorders, or patients receiving anticoagulant therapy; severe heart failure, renal or hepatic impairment; child <18 yrs; pregnancy (third trimester).

Storage

Oral: Store at or below 25°C

Lab interference

Oral: Store at or below 25°C

Dexibuprofen brands in India:

Brutek Brutek-P Dexigesic-P Sibet Sibet P Zeroflam

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