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Clobetasone information from DrugsUpdate  

See Available Brands of Clobetasone in India

P - Contraindicated in pregnancy

Clobetasone is a corticosteroid used in dermatology, for treating such skin inflammation as seen in eczema and other forms of dermatitis, and ophthalmology. It is available as clobetasone butyrate under the brand name Eumovate or Trimovate both manufactured by GlaxoSmithKline.

Pharmacodynamics

Pharmacokinetics

Clobetasone is a corticosteroid with glucocorticoid activity for the treatment of various skin disorders.

Clobetasone Indications / Clobetasone Uses

Information Not Available

Clobetasone Adverse Reactions / Clobetasone Side Effects

Delayed wound healing. Corneal ulcers, raised IOP and reduced visual function (topical application). Na and water retention. Increased excretion of potassium. Ca and phosphorus mobilization with osteoporosis and spontaneous fractures. Increased insulin requirements of diabetics. Increased liability to infection. Infections may be masked. Acute adrenal insufficiency. Growth retardation in child. Cushingoid symptoms. Amenorrhoea, hyperhidrosis, skin thinning, CNS effects, intracranial hypertension, acute pancreatitis, aseptic necrosis of bone.

Precautions

Information Not Available

Special Precautions

May be absorbed in sufficient amounts to cause systemic effects when applied topically to large areas, broken skin or under occlusive dressings. Peptic ulcer, osteoporosis, psychoses or severe psychoneuroses. Not to be used indiscriminately for pruritus. CHF or hypertension. Diabetes mellitus, epilepsy, glaucoma, infectious diseases, ocular herpes simplex, chronic renal failure and uraemia. Active or doubtfully quiescent tuberculosis. Local treatment of eye disorders. Elderly. Prolonged use on the face.

Other Drug Interactions

Live vaccines. Barbiturates, carbamazepine, phenytoin, primidone or rifampicin; thiazide or furosemide. NSAIDs. Anticoagulants. Salicylates. Antimuscarinics.

Other Interactions

Information Not Available

Dosage

Ophthalmic Inflammatory eye disorders
Adult: As eye drops containing 0.1%.


Topical/Cutaneous
Corticosteroid-responsive dermatoses
Adult: Use as 0.05% cream or ointment to be applied thinly once or bid on affected areas.

Food(before/after)

Information Not Available

List of Contraindications

Clobetasone and Pregnancy

Contraindicated in pregnancy

Clobetasone and Lactation

Information Not Available

Clobetasone and Children

Information Not Available

Clobetasone and Geriatic

Information Not Available

Clobetasone and Other Contraindications

Pregnancy (in high doses). Presence of acute infections. Treatment of rosacea; leg ulcers; acne vulgaris; widespread plaque psoriasis. Child <1 year.

Storage

Information Not Available

Lab interference

Information Not Available

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