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Xylometazoline Hydrochloride information from DrugsUpdate  

See Available Brands of Xylometazoline Hydrochloride in India

P - Caution when used during pregnancy
L - Caution when used during lactation

Information Not Available

Pharmacodynamics

Pharmacokinetics

Xylometazoline is a direct-acting sympathomimetic which has a vasoconstrictor effect by reducing swelling and congestion when applied to mucous membranes.

Onset

5-10 minutes.

Duration
10 hours.

Xylometazoline Hydrochloride Indications / Xylometazoline Hydrochloride Uses

Information Not Available

Xylometazoline Hydrochloride Adverse Reactions / Xylometazoline Hydrochloride Side Effects

Headache, insomnia, tachycardia, hypertension, nervousness, nausea, dizziness, palpitation, arrhythmia. Nasal drops: Local stinging or burning, sneezing, dryness of mouth and throat, nausea. Eye drops: Dryness of eye.

Precautions

Information Not Available

Special Precautions

Young children, pregnancy and lactation. Hypertension, CV abnormalities, DM, hyperthyroidism, history of excessive reaction to sympathomimetics, difficulty in urination secondary to prostate enlargement. Rebound congestion may occur after prolonged regular use.

Other Drug Interactions

Increased heart rate or BP with sibutramine.

Potentially Fatal: Hypertensive crisis with MAOIs.

Other Interactions

Information Not Available

Dosage

Ophthalmic
Conjunctival decongestant
Adult: As 0.05-0.1% solution: Instil into the eye.

Nasal
Nasal congestion
Adult: As 0.1% solution: Instill into each nostril bid-tid. Max duration: 7 days.
Child: As 0.05% solution: 3 months-12 years: 1-2 drops into each nostril once or bid. Max duration: 7 days.

Food(before/after)

Information Not Available

List of Contraindications

Xylometazoline Hydrochloride and Pregnancy

Caution when used during pregnancy

Xylometazoline Hydrochloride and Lactation

Caution when used during lactation

Xylometazoline Hydrochloride and Children

Information Not Available

Xylometazoline Hydrochloride and Geriatic

Information Not Available

Xylometazoline Hydrochloride and Other Contraindications

Angle closure glaucoma; dry rhinitis; post trans-sphenoidal hypophysectomy, trans-nasal, trans-oral surgery where dura mater is exposed.

Storage

Nasal
Store below 30°C.

Ophthalmic
Store below 30°C.

Lab interference

Nasal
Store below 30°C.

Ophthalmic
Store below 30°C.

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