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Clobetasol Propionate information from DrugsUpdate  

1
See Available Brands of Clobetasol Propionate in India

P - Caution when used during pregnancy

Clobetasol propionate is a corticosteroid used to treat various skin disorders including eczema and psoriasis. It is also highly effective for contact dermatitis caused by exposure to poison ivy/oak.

Pharmacodynamics

Clobetasol is a very potent corticosteroid used in short-term treatment of various inflammatory skin conditions.

Clobetasol Propionate Indications / Clobetasol Propionate Uses

Topical/Cutaneous
Corticosteroid-responsive dermatoses
Adult: As propionate: Apply 0.05% cream/ointment onto affected area twice daily.
Elderly: Initiate with lower dose.
Renal impairment: Initiate with lower dose.
Hepatic impairment: Initiate with lower dose.

Clobetasol Propionate Adverse Reactions / Clobetasol Propionate Side Effects

Perioral dermatitis, striae esp in flexures. Dermal and epidermal atrophy esp on the face, steroid purpura.


Potentially Fatal: Prolonged usage of large amount of clobetasol propionate can lead to sufficient systemic levels to produce adrenal suppression, Cushing's syndrome, diabetes and hypertension.

Precautions

Information Not Available

Special Precautions

Heart failure, recent myocardial infarction, hypertension; diabetes mellitus; epilepsy; glaucoma; hypothyroidism; hepatic failure, renal impairment; psychoses; childn and elderly. Should not enter eyes. If infection exists, treat with specific anti-infectives. Pregnancy, lactation.

Other Drug Interactions

Information Not Available

Other Interactions

Information Not Available

Dosage

Topical/Cutaneous
Corticosteroid-responsive dermatoses
Adult: As propionate: Apply 0.05% cream/ointment onto affected area twice daily.
Elderly: Initiate with lower dose.

Renal impairment: Initiate with lower dose.
Hepatic impairment: Initiate with lower dose.

Food(before/after)

Information Not Available

List of Contraindications

Clobetasol Propionate and Pregnancy

Caution when used during pregnancy

Clobetasol Propionate and Lactation

Information Not Available

Clobetasol Propionate and Children

Information Not Available

Clobetasol Propionate and Geriatic

Information Not Available

Clobetasol Propionate and Other Contraindications

Children <12 years. Long-term treatment of ulcerative conditions, rosacea, pruritus; presence of acute infections. Hypersensitivity.

Storage

Topical/Cutaneous
Store below 25°C.

Lab interference

Topical/Cutaneous
Store below 25°C.

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