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Silymarin information from DrugsUpdate  

See Available Brands of Silymarin in India

P - Contraindicated in pregnancy
L - Contraindicated in lactation

Silymarin, an antioxidant flavonoid complex derived from the herb milk thistle (Silybum marianum), has long been used as a liver tonic. Two new studies show that it can reduce insulin resistance (the underpinning of adult-onset diabetes, hypertension, and hypercholesterolemia) and diabetic complications. A third study reports that it may have some anti-cancer benefits as well.

Pharmacodynamics

Pharmacokinetics

Silymarin is an active principle from the fruit of Silybum marianum, which contains a mixture of flavonolignans. It reduces the turnover of membrane phospholipids and stabilises the cell membranes of hepatocytes. It has potent antioxidant action and prevents lipid peroxidation.

Silymarin Indications / Silymarin Uses

Information Not Available

Silymarin Adverse Reactions / Silymarin Side Effects

Occasional laxative effects. Abdominal bloating, diarrhoea, flatulence, loss of appetite, anorexia, nausea, stomach upset.

Precautions

Information Not Available

Special Precautions

Children

Other Drug Interactions

Information Not Available

Other Interactions

Information Not Available

Dosage

Oral
Hepatic diseases
Adult: 140 mg bid/tid.

Food(before/after)

Should be taken with food. (Take after meals.)

List of Contraindications

Silymarin and Pregnancy

Contraindicated in pregnancy

Silymarin and Lactation

Contraindicated in lactation

Silymarin and Children

Information Not Available

Silymarin and Geriatic

Information Not Available

Silymarin and Other Contraindications

Hypersensitivity, pregnancy, lactation

Storage

Information Not Available

Lab interference

Information Not Available

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