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Rupatadine information from DrugsUpdate  

See Available Brands of Rupatadine in India

P - Caution when used during pregnancy
L - Caution when used during lactation

Rupatadine is a second generation antihistamine and PAF antagonist used to treat allergies. It was discovered and developed by J. Uriach y Cia, S. A. and is marketed under several trade names such as Rupafin, Alergoliber, Rinialer, Pafinur, Rupax and Ralif.

Pharmacodynamics

Pharmacokinetics

Rupatadine acts as a long-acting, non-sedative antagonist at histaminergic H1-receptors. Rupatadine also antagonises the platelet-activating factor (PAF). Both histamine and PAF cause bronchoconstriction and lead to an increase in the vascular permeability, acting as mediators in the inflammatory process.

Metabolism

Liver - mainly by CYP450.

Rupatadine Indications / Rupatadine Uses

Information Not Available

Rupatadine Adverse Reactions / Rupatadine Side Effects

Headache, somnolence, fatigue/asthenia

Precautions

Information Not Available

Special Precautions

Renal or hepatic insufficiency. May impair ability to drive or operate machinery. Pregnancy, lactation. Elderly, children <12 years.

Other Drug Interactions

Increased CNS depressant effects when used with CNS depressants or alcohol.

Other Interactions

Information Not Available

Dosage

Oral
Allergic rhinitis, Chronic idiopathic urticaria
Adult: 10 mg once daily.

Food(before/after)

Information Not Available

List of Contraindications

Rupatadine and Pregnancy

Caution when used during pregnancy

Rupatadine and Lactation

Caution when used during lactation

Rupatadine and Children

Information Not Available

Rupatadine and Geriatic

Information Not Available

Rupatadine and Other Contraindications

Hypersensitivity. Avoid alcohol

Storage

Information Not Available

Lab interference

Information Not Available

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