Oxymetazoline information from DrugsUpdate  

Pharmacodynamics

Pharmacokinetics

Oxymetazoline is a direct-acting sympathomimetic which has vasoconstrictor effect on mucosal blood vessels when applied topically and in turn reduces oedema of the nasal mucosa.

Duration
Up to 12 hours.

Oxymetazoline Indications / Oxymetazoline Uses

Information Not Available

Oxymetazoline Adverse Reactions / Oxymetazoline Side Effects

Nasal drops or spray: Local stinging or burning, sneezing, dryness of mouth and throat. Prolonged or frequent use may cause rebound congestion. Headache, insomnia, tachycardia, hypertension, nervousness, nausea, dizziness, palpitation, arrhythmia. Eye drops: Dryness of eye.

Precautions

Information Not Available

Special Precautions

Pregnancy, lactation. Difficulty in urination secondary to prostate enlargement; DM.

Other Drug Interactions

Information Not Available

Other Interactions

Information Not Available

Dosage

Ophthalmic
Conjunctival decongestant
Adult: Instil 1-2 drops of 0.025% solution into the eye(s) 6 hourly when necessary.
Child: ≥6 years: Instill 1-2 drops of 0.025% solution into the eye(s) 6 hourly when necessary.

Nasal
Nasal congestion
Adult: As 0.05% solution: Spray 1-3 times into each nostril bid.
Child: ≥6 years: Instill or spray 0.05% solution 1-3 times into each nostril bid.

Food(before/after)

Information Not Available

Oxymetazoline and Pregnancy

Caution when used during pregnancy

Oxymetazoline and Lactation

Caution when used during lactation

Oxymetazoline and Children

Information Not Available

Oxymetazoline and Geriatic

Information Not Available

Oxymetazoline and Other Contraindications

Glaucoma; hyperthyroidism, heart disease (including angina), hypertension, advanced arteriosclerotic conditions. Children <6 years.

Storage

Information Not Available

Lab interference

Information Not Available