Oxymetazoline information from DrugsUpdate
L - Caution when used during lactation
Oxymetazoline is an adrenergic used as the hydrochloride salt as a vasoconstrictor to reduce nasal or conjunctival congestion.
Oxymetazoline is a direct-acting sympathomimetic which has vasoconstrictor effect on mucosal blood vessels when applied topically and in turn reduces oedema of the nasal mucosa.
Up to 12 hours.
Nasal drops or spray: Local stinging or burning, sneezing, dryness of mouth and throat. Prolonged or frequent use may cause rebound congestion. Headache, insomnia, tachycardia, hypertension, nervousness, nausea, dizziness, palpitation, arrhythmia. Eye drops: Dryness of eye.
Pregnancy, lactation. Difficulty in urination secondary to prostate enlargement; DM.
Adult: Instil 1-2 drops of 0.025% solution into the eye(s) 6 hourly when necessary.
Child: ≥6 years: Instill 1-2 drops of 0.025% solution into the eye(s) 6 hourly when necessary.
Adult: As 0.05% solution: Spray 1-3 times into each nostril bid.
Child: ≥6 years: Instill or spray 0.05% solution 1-3 times into each nostril bid.
List of Contraindications
Caution when used during pregnancy
Caution when used during lactation
Glaucoma; hyperthyroidism, heart disease (including angina), hypertension, advanced arteriosclerotic conditions. Children <6 years.
Available brands of Oxymetazoline
- Naselin (Cipla)
- Nasivion (Merck)
- Nasivion Mini (Merck)
- Nasivion Paed (Merck)
- Otrivin-O (Novartis India)
- Oxylin (Allergan)
- Oxyspray (Zydus (G. Rem))
- Rhinojet (Merck)
- Sinarest Nasal DPS (Centaur (Samruddhi))
- Sinarest-PD (Centaur (Shashvatam))
- Sudin Nasal DPS (Group)
- Xynose (Zy. Cadila (Liva))
- Ymetlo (Sanify )
- Zoamet (East India)