Mosapride information from DrugsUpdate
Mosapride is a gastroprokinetic agent that acts as a selective 5HT4 agonist which accelerates gastric emptying and is used for the treatment of acid reflux, irritable bowel syndrome and functional dyspepsia.
Mosapride is a 5-HT4 receptor agonist which increases the release of acetylcholine and stimulates GI motility. It also has 5-HT3 antagonist properties.
Diarrhoea, abdominal pain; dizziness; constipation; headache; insomnia; nausea.
Continuous admin of this drug is not recommended if no improvement in GI symptoms is observed after 2 weeks of admin. Elderly, renal impairment, hepatic impairment.
Mosapride concentration increased by erythromycin. May increase risk of QT prolongation with QT prolonging drugs.
Disorders associated with reduced gastrointestinal motility
Adult: As anhydrous citrate: 5 mg tid.
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