logo image

Atorvastatin + Ezetimibe information from DrugsUpdate  

See Available Brands of Atorvastatin + Ezetimibe in India

P - Contraindicated in pregnancy
L - Contraindicated in lactation

Information Not Available



Atorvastatin competitively inhibits HMG-CoA reductase, the enzyme that catalyses the conversion of HMG-CoA to mevalonate which is an early rate-limiting step in cholesterol biosynthesis. Ezetimibe inhibits the absorption of cholesterol from the intestine, thus decreasing the delivery of intestinal cholesterol to the liver.

Atorvastatin + Ezetimibe Indications / Atorvastatin + Ezetimibe Uses

Information Not Available

Atorvastatin + Ezetimibe Adverse Reactions / Atorvastatin + Ezetimibe Side Effects

Headache, flatulence, dyspepsia, myalgia, rash, pruritus, allergy and infection. Abdominal discomfort, asthenia, constipation, diarrhoea, back pain, arthralgia, resp infection and fatigue.


Information Not Available

Special Precautions

Hepatic impairment; patients consuming substantial quantities of alcohol with a history of liver disease. Not recommended for use in children <10 years.

Other Drug Interactions

Atorvastatin: Increases digoxin levels; increases anticoagulant effect of warfarin. Avoid the combination of HMG-CoA reductase inhibitors and fibrates. Ezetimibe: Cholestyramine decreases AUC of ezetimibe by approx 55%; ciclosporin may increase ezetimibe levels.

Potentially Fatal: Antacids decrease atorvastatin levels; colestipol decreases atorvastatin plasma levels; propranolol decreases antihyperlipidaemic activity of atorvastatin.

Other Interactions

Information Not Available


Adult: Per tablet contains atorvastatin 10 mg and ezetimibe 10 mg: Usual starting: 1 tablet once daily.


Information Not Available

List of Contraindications

Atorvastatin + Ezetimibe and Pregnancy

Contraindicated in pregnancy

Atorvastatin + Ezetimibe and Lactation

Contraindicated in lactation

Atorvastatin + Ezetimibe and Children

Information Not Available

Atorvastatin + Ezetimibe and Geriatic

Information Not Available

Atorvastatin + Ezetimibe and Other Contraindications

Hypersensitivity; active liver disease or unexplained persistent elevated liver function tests. Pregnancy and lactation.


Information Not Available

Lab interference

Information Not Available

© 2011-2018 DrugsUpdate.com. Disclaimer | Site Map