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Ambroxol information from DrugsUpdate  

See Available Brands of Ambroxol in India

P - Caution when used during pregnancy.

Ambroxol is a clinically proven systemically active mucolytic agent. When administered orally onset of action occurs after about 30 minutes. The breakdown of acid mucopolysaccharide fibers makes the sputum thinner and less viscous and therefore more easily removed by coughing. Although sputum volume eventually decreases, its viscosity remains low for as long as treatment is maintained.

Pharmacodynamics

Pharmacokinetics

Alteplase initiates local fibrinolysis and dissolution of clots by binding to fibrin in a thrombus and the fibrin-bound plasminogen is converted to plasmin.

Excretion
Cleared rapidly from the plasma mainly by hepatic metabolism. Half-life: 4-5 minutes (initial); about 40 minutes (terminal).

Ambroxol Indications / Ambroxol Uses

Information Not Available

Ambroxol Adverse Reactions / Ambroxol Side Effects

Mind GI effects & allergic reactions

Precautions

Information Not Available

Special Precautions

Information Not Available

Other Drug Interactions

Information Not Available

Other Interactions

Information Not Available

Dosage

Oral
Mucolytic: Adult- 60-120mg daily in two-three divided doses. Child- <2 years: 7.5 mg bid; 2-5 years 7.5 mg bid/tid; 6-12 years: 15mg bid/tid.

Food(before/after)

Information Not Available

List of Contraindications

Ambroxol and Pregnancy

Caution when used during pregnancy.


Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.

Ambroxol and Lactation

Information Not Available

Ambroxol and Children

Information Not Available

Ambroxol and Geriatic

Information Not Available

Ambroxol and Other Contraindications

There are no absolute contraindications but in patients with gastric ulceration relative caution should be observed.

Storage

Store at a temperature not exceeding 30 degrees celsius

Lab interference

Store at a temperature not exceeding 30 degrees celsius

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