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Mepyramine maleate information from DrugsUpdate  

See Available Brands of Mepyramine maleate in India

Mepyramine maleate, also called as pyrilamine, is a first-generation anti-histaminic drug that antagonizes H1 receptors. Mepyramine maleate is indicated for the treatment of systemic hypersensitivity and pruritic skin disorders. Cream formulations of Mepyramine maleate is prescribed for the symptomatic management of nettle rash and insect bites or stings.

Pharmacodynamics

The drug binds with G-protein coupled receptor associated with H1 receptors that interfere with Gq/11-mediated signaling. Mepyramine maleate competitively binds with the active site of receptors present on the effector cell surface. The sedating property of Mepyramine maleate is associated with sub-cortical levels of the brain.

Pharmacokinetics

No information available

Mepyramine maleate Indications / Mepyramine maleate Uses

No information available

Mepyramine maleate Adverse Reactions / Mepyramine maleate Side Effects

Mepyramine maleate can cause sensitization or allergic skin reactions with pruritus.

Precautions

Mepyramine maleate should not be used in sunburnt skin, eczema and abrasive skin or open wounds.

Do not drive vehicles or operate heavy machineries while taking Mepyramine maleate.

Special Precautions

No information available

Other Drug Interactions

No information available

Other Interactions

No information available

Dosage

The dosage and duration of Mepyramine maleate should be as prescribed by a physician.

Food(before/after)

Take Mepyramine maleate after food intake

List of Contraindications

Mepyramine maleate and Pregnancy

USFDA pregnancy category C. May be or may not be harmful to an unborn baby. Consult your doctor if you are in gestation or planning to have a baby during Mepyramine maleate treatment.

Mepyramine maleate and Lactation

Nursing mothers should consult a physician before taking Mepyramine maleate

Mepyramine maleate and Children

Mepyramine maleate should not be used in children unless prescribed by a pediatrician

Mepyramine maleate and Geriatic

No information available

Mepyramine maleate and Other Contraindications

No information available

Storage

No information available

Lab interference

No information available

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