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Difluprednate information from DrugsUpdate  

See Available Brands of Difluprednate in India

Difluprednate, a topical corticosteroid, is indicated for the treatment of inflammation and pain associated with eye surgery. Difluprednate is also indicated for the treatment of endogenous anterior uveitis.

Pharmacodynamics

The structure of Difluprednate is similar to other corticosteroids. The drug inhibits inflammatory response and the drug inhibit prostaglandins and other pro-inflammatory mediators.

Pharmacokinetics

No information available

Difluprednate Indications / Difluprednate Uses

No information available

Difluprednate Adverse Reactions / Difluprednate Side Effects

Some of the commonly reported adverse events of Difluprednate are thinning of the cornea or sclera, IOP and associated nerve damage, subcapsular cataract, herpetic ocular infection and visual acuity and field defects.

Precautions

Difluprednate is contraindicated in patients with cataract, delayed wound healing disorders, IOP, active infections including viral, fungal and bacterial infections and individuals wearing contact lens.

Special Precautions

No information available

Other Drug Interactions

Avoid using Difluprednate with topical corticosteroid formulations

Other Interactions

No information available

Dosage

For ocular surgery (Adults):
Instil one drop of Difluprednate into the conjunctival sac (affected eye), four times a day on the first day of surgery. The treatment should be continued for at least two weeks during the post-operative period. Then the dose can be tapered to twice daily.
 
For treatment of endogenous anterior uveitis (Adults):
Instil one drop of Difluprednate into the conjunctival sac (affected eye), four times a day. The dosage can be tapered gradually, depending on the treatment response

Food(before/after)

No information available

List of Contraindications

Difluprednate and Pregnancy

USFDA pregnancy category C. May be or may not be harmful to an unborn baby. Consult your doctor if you are in gestation or planning to have a baby during Difluprednate treatment.

Difluprednate and Lactation

Nursing mothers should consult a physician before using Difluprednate.

Difluprednate and Children

Difluprednate should not be used in children unless prescribed by a pediatrician

Difluprednate and Geriatic

No information available

Difluprednate and Other Contraindications

No information available

Storage

No information available

Lab interference

No information available

Difluprednate brands in India:

Baklot Enpred Flupred

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